Free Estradiol is avail at both Quest and LabCorp, it might be an eye opener for you. Where you see your Free T close to the lab range you can reasonably be assured that Free E is also up there. SHBG binds to E just like it does to T, you have a lower amount (more than me, I run ~12) of binding material so your free hormones are up there.
Twice daily injections is something I considered. But I'm actually in a very good spot right now with my protocol and besides some ED that lingers, things are way better now than I've ever been.
If you wanted EOD, just start low and work up...I did a long history over months time of 2mg at a time. I'd so 16mg EOD and see where you're at.