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It's possible it was lowering before already, but I was feeling fine and it was a pretty profound change after the caffeine reaction. But yea, I think probably Hydrocortisone over Prednisone though, as the latter is very strong.



Years back I have taken HC "as needed" when I had low mood/anxiety symptoms and on some days it would help and I'd basically be cured for the day while on other days it would make it worse, it was very random what would happen. But this time my symptom is very different, somehow my phenotype of HPA dysregulation changed over these years (for the worse imo, I think id rather feel low than emotionally blunted).


Since HPA dysfunction is ultimately a "brain issue" I had tried 1 Ketamine infusion (attempt at a quick fix) a couple weeks ago to try to reset it, but it actually worsened my symptoms for about a week so that option is off the list. Ketamine is for depression, and it wasn't totally clear if it would help this isolated symptom but there are anecdotes of it bringing back emotions but for me it was the opposite.


One issue I have had forever though is low cholesterol. My total cholesterol right now is around 105. I wonder if somehow this is the root for all these issues. I've never figured out why its so low, its partly genetic but even in my family people have levels of like 130, so I might be having malabsorption or something. I think I might need to investigate the gut too.


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