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I was on beta blockers for a while, mostly to control migraines. Started with propranolol, and due to side effects, switched to bystolic. I was under the impression from what I read bystolic was much less likely to cause side effects, and I actually perceived it to be the case in my self.


However, over the course of time, I developed gradual, sometimes severe depression, and was very fatigued. Based purely on the subjective experience, it’s hard for me to recommend beta blockers unless there’s a specific medical indication. They can be miracle drugs for the right indication. I sometimes cut a propranolol in half and use it here and there when TRT drives up anxiety. In small doses I think this is safe.


I would consider an ARB over a beta blocker unless there’s a specific medical reason why a beta blocker makes better sense for you.


TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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