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Message: <blockquote data-quote="Gman86" data-source="post: 131906" data-attributes="member: 15043">Good point. It probably is difficult to stay dialed in. But i think for most guys, the range at which they are going to feel optimal is fairly wide. Although, some guys do report noticing negative symptoms if their E2 goes up 5-10 points. I feel bad for those guys. That must be very difficult. But I think, for most men, there’s probably a 20 point gap that you can stay in without feeling too many negative side effects, which I don’t think would be extremely hard to maintain.Me, personally, I’m shooting for around 30-50, for my total E2.</blockquote>