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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Blood work and Natesto
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<blockquote data-quote="madman" data-source="post: 224871" data-attributes="member: 13851"><p>Nothing to do with the Natesto as there is no buildup/steady-state achieved due to its fast-acting nature.</p><p></p><p>In/out of your system quick!</p><p></p><p>Natesto would be considered the least suppressive to the HPTA due to the short-lived peaks/significant trough times between doses.</p><p></p><p>Regardless of whether dosing 2-3 times daily, there is a short-lived peak Tmax 40-60 min <em>(t1/2 ~1h)</em> with long trough times 6-8 hrs between doses.</p><p></p><p>The reason your testosterone is higher on your most recent labs (2nd) is that you had it tested in the early am when your levels will be at peak (highest) during the 24 hr circadian rhythm.</p><p></p><p>Hopefully, you also fasted otherwise your levels would have been higher.</p><p></p><p>Critical that blood work is done in a fasted state in the early am as we want to test at the peak.</p><p></p><p>Top it off that if you strength train then I would strongly recommend taking a week off so you are well rested/recovered as excess stress whether (mental/physical), let alone lack of quality sleep can hammer down T levels!</p><p></p><p>The sad fact of the matter is your TT 433 ng/dL at the peak is far from anything to brag about and more importantly, your FT would be sub-par.</p><p></p><p>Although TT is important to know FT is what truly matters as it is the active unbound fraction of testosterone responsible for the positive effects.</p><p></p><p>Always best to have blood work done twice over the course of a few weeks in the early am/fasted and take a week off from the gym if you strength train.</p><p></p><p></p><p><strong><em>*Do not make a diagnosis of AD (androgen deficiency) based on a single T measurement or only on T level</em></strong></p><p><strong><em></em></strong></p><p><strong><em></em></strong></p><p><strong><em></em></strong></p><p><strong><em></em></strong></p><p><strong><em>post #9</em></strong></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/testosterone-blood-test-results-time-of-day.25321/#post-224483[/URL]</p></blockquote><p></p>
[QUOTE="madman, post: 224871, member: 13851"] Nothing to do with the Natesto as there is no buildup/steady-state achieved due to its fast-acting nature. In/out of your system quick! Natesto would be considered the least suppressive to the HPTA due to the short-lived peaks/significant trough times between doses. Regardless of whether dosing 2-3 times daily, there is a short-lived peak Tmax 40-60 min [I](t1/2 ~1h)[/I] with long trough times 6-8 hrs between doses. The reason your testosterone is higher on your most recent labs (2nd) is that you had it tested in the early am when your levels will be at peak (highest) during the 24 hr circadian rhythm. Hopefully, you also fasted otherwise your levels would have been higher. Critical that blood work is done in a fasted state in the early am as we want to test at the peak. Top it off that if you strength train then I would strongly recommend taking a week off so you are well rested/recovered as excess stress whether (mental/physical), let alone lack of quality sleep can hammer down T levels! The sad fact of the matter is your TT 433 ng/dL at the peak is far from anything to brag about and more importantly, your FT would be sub-par. Although TT is important to know FT is what truly matters as it is the active unbound fraction of testosterone responsible for the positive effects. Always best to have blood work done twice over the course of a few weeks in the early am/fasted and take a week off from the gym if you strength train. [B][I]*Do not make a diagnosis of AD (androgen deficiency) based on a single T measurement or only on T level post #9[/I][/B] [URL unfurl="true"]https://www.excelmale.com/forum/threads/testosterone-blood-test-results-time-of-day.25321/#post-224483[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Blood work and Natesto
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