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Hi txcajun, welcome to the forum!

Your RBC, Hemoglobin, and Hematocrit are on the high side for someone not on TRT or on AAS. Do you live at a high altitude? How is your sleep? Do you have sleep apnea?

You have extremely high SHBG (Sex Hormone Binding Globulin) at 84.5. Your Total T at 871 is not bad in just looking at the number itself, but it being bound up by that large amount of SHBG leaving you little Free T. Your Free T is below mid range and is only accounting for 1.15% of your Total T. Most men have Free T levels at 2% to 3%%. Your bioavailable testosterone is only sitting at 28%. If your SHBG wasn't so high and was within a normal range you would probably be fine.

Your TSH, while, within range, is too high. Your Free T4 is a little on the low side and should be close to 1.7 and your Free T3 is not optimal either and should be at 3.8. Although they too are within range they are indicating there could be a thyroid issue. I would have a full thyroid panel work up to include the following: TSH, Free T3, Free T4, Reverse T3, and both Thyroid antibodies (TPOab and TgAB). An under performing thyroid will give you low T symptoms.

It appears that the Estradiol test is the wrong one just based off the range. You labs don't specifically state which test was used. I am betting it was the Roche ECLIA methodology which is the test for women. Men need the Estradiol Sensitive LC/MS/MS assay. Because it is more sensitive it an properly estimate the lower estradiol levels in men.

Once again, welcome to ExcelMale.

<blockquote data-quote="MarkM" data-source="post: 122256">Hi txcajun, welcome to the forum!Your RBC, Hemoglobin, and Hematocrit are on the high side for someone not on TRT or on AAS.&nbsp; Do you live at a high altitude? How is your sleep?&nbsp; Do you have sleep apnea? You have extremely high SHBG (Sex Hormone Binding Globulin) at 84.5.&nbsp; Your Total T at 871 is not bad in just looking at the number itself, but it being bound up by that large amount of SHBG leaving you little Free T.&nbsp; Your Free T is below mid range and is only accounting for 1.15% of your Total T.&nbsp; Most men have Free T levels at 2% to 3%%.&nbsp; Your bioavailable testosterone is only sitting at 28%.&nbsp; If your SHBG wasn&#039;t so high and was within a normal range you would probably be fine.Your TSH, while, within range, is too high.&nbsp; Your Free T4 is a little on the low side and should be close to 1.7 and your Free T3 is not optimal either and should be at 3.8.&nbsp; Although they too are within range they are indicating there could be a thyroid issue.&nbsp; I would have a full thyroid panel work up to include the following:&nbsp; TSH, Free T3, Free T4, Reverse T3, and both Thyroid antibodies (TPOab and TgAB).&nbsp; An under performing thyroid will give you low T symptoms.&nbsp; It appears that the Estradiol test is the wrong one just based off the range.&nbsp; You labs&nbsp; don&#039;t specifically state which test was used.&nbsp; I am betting it was the Roche ECLIA methodology which is the test for women.&nbsp; Men need the Estradiol Sensitive LC/MS/MS assay.&nbsp; Because it is more sensitive it an properly estimate the lower estradiol levels in men.&nbsp; Once again, welcome to ExcelMale.</blockquote>

[QUOTE="MarkM, post: 122256"] Hi txcajun, welcome to the forum! Your RBC, Hemoglobin, and Hematocrit are on the high side for someone not on TRT or on AAS. Do you live at a high altitude? How is your sleep? Do you have sleep apnea? You have extremely high SHBG (Sex Hormone Binding Globulin) at 84.5. Your Total T at 871 is not bad in just looking at the number itself, but it being bound up by that large amount of SHBG leaving you little Free T. Your Free T is below mid range and is only accounting for 1.15% of your Total T. Most men have Free T levels at 2% to 3%%. Your bioavailable testosterone is only sitting at 28%. If your SHBG wasn't so high and was within a normal range you would probably be fine. Your TSH, while, within range, is too high. Your Free T4 is a little on the low side and should be close to 1.7 and your Free T3 is not optimal either and should be at 3.8. Although they too are within range they are indicating there could be a thyroid issue. I would have a full thyroid panel work up to include the following: TSH, Free T3, Free T4, Reverse T3, and both Thyroid antibodies (TPOab and TgAB). An under performing thyroid will give you low T symptoms. It appears that the Estradiol test is the wrong one just based off the range. You labs don't specifically state which test was used. I am betting it was the Roche ECLIA methodology which is the test for women. Men need the Estradiol Sensitive LC/MS/MS assay. Because it is more sensitive it an properly estimate the lower estradiol levels in men. Once again, welcome to ExcelMale. [/QUOTE]

Verification

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038