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Yet my cortisol is average and at 68 years old and osteoarthritis in most of my joints, I am lucky to just go to the gym at all.   My cardiologist knew the answer to this one, and it he said it was a normal response in the circadian cycle.  From 3-4am there is a sharp increase in blood pressure and the heart rate starts to rise.  The morning is also when most people have heart attacks.  One theory looks at a protein in your blood called  plasminogen activator inhibitor 1(PA1), which prevents clots from dissolving.   There is also a sharp increase in PA1 levels.  My resting HR is normally 63bpm and it drops to 52bpm during the night.


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