ExcelMale
Menu
Home
What's new
Latest activity
Forums
New posts
Search forums
What's new
New posts
Latest activity
Videos
Lab Tests
Doctor Finder
Buy Books
About Us
Men’s Health Coaching
Log in
Register
What's new
Search
Search
Search titles only
By:
New posts
Search forums
Menu
Log in
Register
Navigation
Install the app
Install
More options
Contact us
Close Menu
Forums
General Health & Fitness
Workouts & Routines
Beginner weight lifting questions?
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Message
<blockquote data-quote="BigTex" data-source="post: 278229" data-attributes="member: 43589"><p>.</p><p></p><p></p><p></p><p>There are two forms of hypertrophy thought to increase muscular size, 1) myofibrilr and 2) sarcoplasmic. Myofibril hypertrophy refers to an increase in the size and strength of myofibrils within muscle fibers. Myofibrils are the contractile units of muscle cells, composed mainly of two types of protein filaments: actin and myosin. These filaments slide past each other during muscle contraction, generating force and causing muscle to shorten. This usually happens with lower reps (1-5) and heavier weight.</p><p></p><p>Sarcoplasmic hypertrophy refers to an increase in the volume of the sarcoplasm, the fluid-filled space surrounding the myofibrils within muscle fibers. Unlike myofibril hypertrophy, which involves the enlargement and strengthening of the contractile units within the muscle fibers, sarcoplasmic hypertrophy primarily focuses on increasing the non-contractile components of muscle cells. This is typically known as the pump you get in the gym doing moderate weight with higher reps between 6-12.</p><p></p><p>So science has determined that training with lower reps and heavy weight you will get a denser muscle and lots of strength. Training with lighter weight and reps or 6-12 you get a lot of sarcoplasmic hypertrophy so the muscle won’t be as functionally strong but it will be much larger. Which explains the difference between body builders and powerlifters.</p><p></p><p></p><p>[ATTACH=full]42877[/ATTACH]</p><p></p><p></p><p><strong>Cialis</strong></p><p></p><p>Cialis is in the class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. What these drugs do is 1st is increase blood flow. This is the main effect of Cialis, and it’s simple: get the blood flowing more efficiently by relaxing the blood vessels. When we increase blood flow while training with moderate weight using 6-12 reps, we also increase blood flow, thus shuttle more nutrients into the muscle, super saturating the muscle cell thus creating what we know as the pump. This is though to kickstart hypertrophy. So yes, taking Cialis or even Viagra before you train can also help with the pump. Bodybuilder have been doing this for a while now.</p><p></p><p><strong>Fat Loss</strong></p><p></p><p>There is some evidence in rat studies that PDEe5 inhibitors like Cialis will help with fat loss. One proposed mechanism for potential fat loss with PDE5 inhibitors involves the activation of cyclic guanosine monophosphate (cGMP) pathways. PDE5 inhibitors work by blocking the enzyme PDE5, which normally breaks down cGMP. By inhibiting PDE5, these drugs increase levels of cGMP, leading to vasodilation and increased blood flow. Additionally, cGMP can affect various cellular processes, including metabolism.</p><p>Some research suggests that elevated cGMP levels may influence fat metabolism and adipocyte (fat cell) function. Increased cGMP signaling has been associated with the activation of pathways involved in lipolysis, the breakdown of fat stored in adipose tissue. This could potentially lead to increased fat utilization and, in some cases, fat loss.</p><p></p><p><strong>Better testosterone/estrogen ratio</strong></p><p></p><p>One proposed mechanism for how Cialis might affect testosterone/estrogen ratios involves its ability to increase levels of cyclic guanosine monophosphate (cGMP). PDE5 inhibitors like Cialis work by inhibiting the enzyme PDE5, which breaks down cGMP. Elevated levels of cGMP can influence various cellular processes, including hormone production and signaling pathways.</p><p></p><p>Some research suggests that increased cGMP levels, as seen with PDE5 inhibitors, may have effects on hormone regulation. Elevated cGMP levels have been associated with increased testosterone production in some studies. Additionally, there is evidence to suggest that PDE5 inhibitors may have anti-estrogenic effects, potentially leading to a more favorable testosterone/estrogen ratio.</p><p></p><p><strong>Reduced inflammation</strong></p><p></p><p>One proposed mechanism for how Cialis might reduce inflammation involves its ability to modulate the activity of the nitric oxide (NO) pathway. Cialis, like other phosphodiesterase type 5 (PDE5) inhibitors, works by inhibiting the enzyme PDE5, which degrades cyclic guanosine monophosphate (cGMP). Elevated levels of cGMP lead to vasodilation and improved blood flow, which is the primary mechanism behind its efficacy in treating ED.</p><p></p><p>Nitric oxide, a signaling molecule involved in vasodilation, also has anti-inflammatory properties. NO can suppress the expression of pro-inflammatory cytokines and adhesion molecules, inhibit leukocyte adhesion to endothelial cells, and reduce oxidative stress. By enhancing NO signaling through inhibition of PDE5, Cialis may exert anti-inflammatory effects.</p><p></p><p>Some studies have suggested that PDE5 inhibitors, including Cialis, may have anti-inflammatory properties beyond their effects on vasodilation. These effects may be particularly relevant in conditions where inflammation plays a significant role, such as cardiovascular disease and pulmonary hypertension.</p></blockquote><p></p>
[QUOTE="BigTex, post: 278229, member: 43589"] . There are two forms of hypertrophy thought to increase muscular size, 1) myofibrilr and 2) sarcoplasmic. Myofibril hypertrophy refers to an increase in the size and strength of myofibrils within muscle fibers. Myofibrils are the contractile units of muscle cells, composed mainly of two types of protein filaments: actin and myosin. These filaments slide past each other during muscle contraction, generating force and causing muscle to shorten. This usually happens with lower reps (1-5) and heavier weight. Sarcoplasmic hypertrophy refers to an increase in the volume of the sarcoplasm, the fluid-filled space surrounding the myofibrils within muscle fibers. Unlike myofibril hypertrophy, which involves the enlargement and strengthening of the contractile units within the muscle fibers, sarcoplasmic hypertrophy primarily focuses on increasing the non-contractile components of muscle cells. This is typically known as the pump you get in the gym doing moderate weight with higher reps between 6-12. So science has determined that training with lower reps and heavy weight you will get a denser muscle and lots of strength. Training with lighter weight and reps or 6-12 you get a lot of sarcoplasmic hypertrophy so the muscle won’t be as functionally strong but it will be much larger. Which explains the difference between body builders and powerlifters. [ATTACH type="full" alt="hypertrophy.jpg"]42877[/ATTACH] [B]Cialis[/B] Cialis is in the class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. What these drugs do is 1st is increase blood flow. This is the main effect of Cialis, and it’s simple: get the blood flowing more efficiently by relaxing the blood vessels. When we increase blood flow while training with moderate weight using 6-12 reps, we also increase blood flow, thus shuttle more nutrients into the muscle, super saturating the muscle cell thus creating what we know as the pump. This is though to kickstart hypertrophy. So yes, taking Cialis or even Viagra before you train can also help with the pump. Bodybuilder have been doing this for a while now. [B]Fat Loss[/B] There is some evidence in rat studies that PDEe5 inhibitors like Cialis will help with fat loss. One proposed mechanism for potential fat loss with PDE5 inhibitors involves the activation of cyclic guanosine monophosphate (cGMP) pathways. PDE5 inhibitors work by blocking the enzyme PDE5, which normally breaks down cGMP. By inhibiting PDE5, these drugs increase levels of cGMP, leading to vasodilation and increased blood flow. Additionally, cGMP can affect various cellular processes, including metabolism. Some research suggests that elevated cGMP levels may influence fat metabolism and adipocyte (fat cell) function. Increased cGMP signaling has been associated with the activation of pathways involved in lipolysis, the breakdown of fat stored in adipose tissue. This could potentially lead to increased fat utilization and, in some cases, fat loss. [B]Better testosterone/estrogen ratio[/B] One proposed mechanism for how Cialis might affect testosterone/estrogen ratios involves its ability to increase levels of cyclic guanosine monophosphate (cGMP). PDE5 inhibitors like Cialis work by inhibiting the enzyme PDE5, which breaks down cGMP. Elevated levels of cGMP can influence various cellular processes, including hormone production and signaling pathways. Some research suggests that increased cGMP levels, as seen with PDE5 inhibitors, may have effects on hormone regulation. Elevated cGMP levels have been associated with increased testosterone production in some studies. Additionally, there is evidence to suggest that PDE5 inhibitors may have anti-estrogenic effects, potentially leading to a more favorable testosterone/estrogen ratio. [B]Reduced inflammation[/B] One proposed mechanism for how Cialis might reduce inflammation involves its ability to modulate the activity of the nitric oxide (NO) pathway. Cialis, like other phosphodiesterase type 5 (PDE5) inhibitors, works by inhibiting the enzyme PDE5, which degrades cyclic guanosine monophosphate (cGMP). Elevated levels of cGMP lead to vasodilation and improved blood flow, which is the primary mechanism behind its efficacy in treating ED. Nitric oxide, a signaling molecule involved in vasodilation, also has anti-inflammatory properties. NO can suppress the expression of pro-inflammatory cytokines and adhesion molecules, inhibit leukocyte adhesion to endothelial cells, and reduce oxidative stress. By enhancing NO signaling through inhibition of PDE5, Cialis may exert anti-inflammatory effects. Some studies have suggested that PDE5 inhibitors, including Cialis, may have anti-inflammatory properties beyond their effects on vasodilation. These effects may be particularly relevant in conditions where inflammation plays a significant role, such as cardiovascular disease and pulmonary hypertension. [/QUOTE]
Insert quotes…
Verification
Post reply
Share this page
Facebook
Twitter
Reddit
Pinterest
Tumblr
WhatsApp
Email
Share
Link
Sponsors
Forums
General Health & Fitness
Workouts & Routines
Beginner weight lifting questions?
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.
Accept
Learn more…
Top