ExcelMale
Menu
Home
What's new
Latest activity
Forums
New posts
Search forums
What's new
New posts
Latest activity
Videos
Lab Tests
Doctor Finder
Buy Books
About Us
Men’s Health Coaching
Log in
Register
What's new
Search
Search
Search titles only
By:
New posts
Search forums
Menu
Log in
Register
Navigation
Install the app
Install
More options
Contact us
Close Menu
Forums
Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Assessment of immunoassay calibrators for T, E2, and P4 using UPLC-MS
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Message
<blockquote data-quote="madman" data-source="post: 255563" data-attributes="member: 13851"><p><em>Manufacturer-supplied calibrators for sex steroid immunoassays often have inaccurate concentrations. Only a small percentage of testosterone, estradiol, and progesterone calibrators meet the 20% margin of stated label concentration. The assigned uncertainties of the calibrators don't encompass the discrepancies. Direct steroid immunoassays show method-specific bias compared to mass spectrometry-based methods. Standardization efforts have been made, but deviations persist. Direct steroid immunoassays have limitations in accuracy and validity. LC-MS-based steroid measurement is desired for better accuracy in clinical practice, but cost and expertise pose challenges.</em></p></blockquote><p></p>
[QUOTE="madman, post: 255563, member: 13851"] [I]Manufacturer-supplied calibrators for sex steroid immunoassays often have inaccurate concentrations. Only a small percentage of testosterone, estradiol, and progesterone calibrators meet the 20% margin of stated label concentration. The assigned uncertainties of the calibrators don't encompass the discrepancies. Direct steroid immunoassays show method-specific bias compared to mass spectrometry-based methods. Standardization efforts have been made, but deviations persist. Direct steroid immunoassays have limitations in accuracy and validity. LC-MS-based steroid measurement is desired for better accuracy in clinical practice, but cost and expertise pose challenges.[/I] [/QUOTE]
Insert quotes…
Verification
Post reply
Share this page
Facebook
Twitter
Reddit
Pinterest
Tumblr
WhatsApp
Email
Share
Link
Sponsors
Forums
Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Assessment of immunoassay calibrators for T, E2, and P4 using UPLC-MS
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.
Accept
Learn more…
Top