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Ask The Urologist Anything (Dr Michael Rotman)
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<blockquote data-quote="nurselyfe" data-source="post: 94511" data-attributes="member: 16355"><p>Dr. Rotman,</p><p></p><p>Background</p><p>24 y.o. healthy male here. I've been on TRT for 3.5 years, was <strong>not</strong> hypogonadic before TRT. Ran into issues this past May when I took way too much Anastrazole, while on 105mg T Cypionate per week. Ever since I did that, I have a myriad of physical and sexual symptoms that I have never had in my life, despite ceasing Anastrazole for over 5 months now, and blood work suggesting perfect health and hormone levels. </p><p></p><p>Symptoms:</p><p>· Complete absence of sebum</p><p>· Dry skin, hair, and mouth with texture changes on skin</p><p>· Severe diffuse head hair loss on entire scalp, from eyebrows, and eye lashes</p><p>· Severe diffuse hair loss on entire body</p><p>· Erectile dysfunction</p><p>· Very low libido</p><p>· Reduction of vascularity</p><p>· Reduction in blood pressure (128/82 to 110/68)</p><p>· Loss of aggression</p><p>· Slowed metabolism</p><p>· Muscle wastage, loss of blood flow to muscles, and inability to increase muscular endurance or strength </p><p>· Reduced appetite </p><p>· Increased body fat</p><p>· Slow nail growth and reduction in quality</p><p>· Cold sweats</p><p>· Cold extremities</p><p></p><p></p><p>Protocol 30mg T Cypionate EOD (~105mg per week)</p><p></p><p>TT 1006 (264-916) </p><p>FT 24.2 (9-26.5)</p><p> E2 35 (7.6-42.6) </p><p>SHBG 31 (16-55.9)</p><p>IGF1 267 (55-355)</p><p>DHEA-S 374.3 (164.3-530)</p><p>TSH 1.4 (.45-4.5)</p><p>fT4 1.26 (.82-1.77)</p><p>fT3 2.8 (2.0-4.4)</p><p>Thyroid Antibodies normal</p><p></p><p>Situation</p><p>Firmly believe I have acquired an estrogen insensitivity via an epigenetic pathway. Regardless if you agree with this or not, I have visited many doctors (endo's and uro's) and they seem to think my symptoms are due to me being on TRT since I did not "need" it to begin with. </p><p></p><p>My question to you, is this correct? Can TRT cause these symptoms? I felt incredible until I crashed my estrogen. I thought TRT is meant to combat these symptoms.</p></blockquote><p></p>
[QUOTE="nurselyfe, post: 94511, member: 16355"] Dr. Rotman, Background 24 y.o. healthy male here. I've been on TRT for 3.5 years, was [B]not[/B] hypogonadic before TRT. Ran into issues this past May when I took way too much Anastrazole, while on 105mg T Cypionate per week. Ever since I did that, I have a myriad of physical and sexual symptoms that I have never had in my life, despite ceasing Anastrazole for over 5 months now, and blood work suggesting perfect health and hormone levels. Symptoms: · Complete absence of sebum · Dry skin, hair, and mouth with texture changes on skin · Severe diffuse head hair loss on entire scalp, from eyebrows, and eye lashes · Severe diffuse hair loss on entire body · Erectile dysfunction · Very low libido · Reduction of vascularity · Reduction in blood pressure (128/82 to 110/68) · Loss of aggression · Slowed metabolism · Muscle wastage, loss of blood flow to muscles, and inability to increase muscular endurance or strength · Reduced appetite · Increased body fat · Slow nail growth and reduction in quality · Cold sweats · Cold extremities Protocol 30mg T Cypionate EOD (~105mg per week) TT 1006 (264-916) FT 24.2 (9-26.5) E2 35 (7.6-42.6) SHBG 31 (16-55.9) IGF1 267 (55-355) DHEA-S 374.3 (164.3-530) TSH 1.4 (.45-4.5) fT4 1.26 (.82-1.77) fT3 2.8 (2.0-4.4) Thyroid Antibodies normal Situation Firmly believe I have acquired an estrogen insensitivity via an epigenetic pathway. Regardless if you agree with this or not, I have visited many doctors (endo's and uro's) and they seem to think my symptoms are due to me being on TRT since I did not "need" it to begin with. My question to you, is this correct? Can TRT cause these symptoms? I felt incredible until I crashed my estrogen. I thought TRT is meant to combat these symptoms. [/QUOTE]
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