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Ask The Urologist Anything (Dr Michael Rotman)
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<blockquote data-quote="jsr0367" data-source="post: 93361" data-attributes="member: 12839"><p>Dr Rotman:</p><p></p><p>I have been on TRT for 3 years now. As far as I can remember my PSA has always been in the 3.5-4.1 range - even before TRTR. Last July my PSA spiked to 5.83 and my urologist stopped TRT and prescribed Bactrim fof 3 weeks. My PSA dropped to 4.1 in a week and at the end of the 4 weeks I was down to 3.83. He restarted TRT in August. Then I noticed that I was putting on body fat and my weight was creeping up. In 4 months I was 7 pounds heavier and bodyfat up 2% (to 14 from 12). I asked my GP for a test for Estradiol in Oct and it was 54. I contacted my urologist and we dropped my Cyp to 120mg per week from 150mg per week IM. I noticed after month feeling more tired and loss of nocturnal erections. So in December we upped my Cyp to 140mg per week and started feeling better around Xmas. Saturday my Urologist ran labs in preparation for my 1/19/18 f/u visit. My PSA is back up to 4.9 I don't know what my Estradiol is because he doesn't test. He only tests for Testosterone, HCT and PSA. HCT is 52.</p><p></p><p>I suspect when I see him this Friday we will be scheduling a biopsy.</p><p></p><p>Looking for some thoughts on this issue. Is there a link between Estradiol and PSA? There seems to be but my urologist dismisses it.</p><p></p><p>Is there anything I should be doing?</p></blockquote><p></p>
[QUOTE="jsr0367, post: 93361, member: 12839"] Dr Rotman: I have been on TRT for 3 years now. As far as I can remember my PSA has always been in the 3.5-4.1 range - even before TRTR. Last July my PSA spiked to 5.83 and my urologist stopped TRT and prescribed Bactrim fof 3 weeks. My PSA dropped to 4.1 in a week and at the end of the 4 weeks I was down to 3.83. He restarted TRT in August. Then I noticed that I was putting on body fat and my weight was creeping up. In 4 months I was 7 pounds heavier and bodyfat up 2% (to 14 from 12). I asked my GP for a test for Estradiol in Oct and it was 54. I contacted my urologist and we dropped my Cyp to 120mg per week from 150mg per week IM. I noticed after month feeling more tired and loss of nocturnal erections. So in December we upped my Cyp to 140mg per week and started feeling better around Xmas. Saturday my Urologist ran labs in preparation for my 1/19/18 f/u visit. My PSA is back up to 4.9 I don't know what my Estradiol is because he doesn't test. He only tests for Testosterone, HCT and PSA. HCT is 52. I suspect when I see him this Friday we will be scheduling a biopsy. Looking for some thoughts on this issue. Is there a link between Estradiol and PSA? There seems to be but my urologist dismisses it. Is there anything I should be doing? [/QUOTE]
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