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<blockquote data-quote="1Draw" data-source="post: 90191" data-attributes="member: 12868"><p>Dr. McClain:</p><p></p><p>Many thanks for taking time to answer questions on this forum. Very rare for a MD of your expertise to do this freely and openly. Very unselfish on your part! Also thanks to Nelson for putting this together for all of us members with some very good questions that we can't find answers for.</p><p></p><p>My questions is I'm a high SHBG guy and have been on T therapy now for almost 3 years. Started out with pellets and have tried most every therapy there is. I'm still looking for the "sweet spot" that is so elusive. I'm currently on .25 ml TCyp with grapeseed oil IM every 3.5 days and no HCG. </p><p></p><p>My hematocrit always jumps up and am having to donate every 8 weeks to keep in line. On my last blood test, my E2 was 60 and was put on exemestane .25 mg 2 x week since I have problems with anastrozole. I'm due for a new blood test in couple weeks and a consult with Defy also. I am very sensitive to AI's in general and would prefer not to take them if at all possible. </p><p></p><p>My question is would a high SHBG guy do well with daily T injections to keep hematocrit and E2 in line? I understand that I would probably have to live with low free T if I do this but to eliminate the need for 7 donations a year and E2 in line without an AI would be priceless for me! Also, what daily dosage would you recommend for someone on 100 mg a week?</p><p></p><p>Many thanks for your reply.</p></blockquote><p></p>
[QUOTE="1Draw, post: 90191, member: 12868"] Dr. McClain: Many thanks for taking time to answer questions on this forum. Very rare for a MD of your expertise to do this freely and openly. Very unselfish on your part! Also thanks to Nelson for putting this together for all of us members with some very good questions that we can't find answers for. My questions is I'm a high SHBG guy and have been on T therapy now for almost 3 years. Started out with pellets and have tried most every therapy there is. I'm still looking for the "sweet spot" that is so elusive. I'm currently on .25 ml TCyp with grapeseed oil IM every 3.5 days and no HCG. My hematocrit always jumps up and am having to donate every 8 weeks to keep in line. On my last blood test, my E2 was 60 and was put on exemestane .25 mg 2 x week since I have problems with anastrozole. I'm due for a new blood test in couple weeks and a consult with Defy also. I am very sensitive to AI's in general and would prefer not to take them if at all possible. My question is would a high SHBG guy do well with daily T injections to keep hematocrit and E2 in line? I understand that I would probably have to live with low free T if I do this but to eliminate the need for 7 donations a year and E2 in line without an AI would be priceless for me! Also, what daily dosage would you recommend for someone on 100 mg a week? Many thanks for your reply. [/QUOTE]
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