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<blockquote data-quote="Marco N Cognito" data-source="post: 88897" data-attributes="member: 13"><p>3 questions for Dr. McClain:</p><p></p><p>1) Have you seen any thyroid suppression with the use of carnitine supplementation for those who are hypothyroid and on thyroid replacement (L-carnitine has been shown in many studies to suppress both T3 and T4 at the cellular level)? If so, do you think taking the thyroid meds hours apart from the carnitine would be an adequate workaround to allow the benefits of carnitine without the thyroid suppression?</p><p> </p><p>2) There is much anecdotal use of the research peptides BPC-157 and TB500 for musculoskeletal issues. Although these compounds are outside the scope of what a physician can prescribe, what's your opinion, if any, on these compounds and what has been your observation with patients using them?</p><p> </p><p>3) I am 57, not on TRT, and produce a total T between the mid 400s-mid 600s, while free T is on the low end of normal, depending on time of draw. Libido seems ok. Have increased joint pain and inflammation lately, but don't know if that's related to T levels. If I did wish to further optimize my levels, would you recommend I try a SERM like clomiphene before 'throwing in the towel' and going with TRT as I would prefer to preserve what endogenous T I have left?</p></blockquote><p></p>
[QUOTE="Marco N Cognito, post: 88897, member: 13"] 3 questions for Dr. McClain: 1) Have you seen any thyroid suppression with the use of carnitine supplementation for those who are hypothyroid and on thyroid replacement (L-carnitine has been shown in many studies to suppress both T3 and T4 at the cellular level)? If so, do you think taking the thyroid meds hours apart from the carnitine would be an adequate workaround to allow the benefits of carnitine without the thyroid suppression? 2) There is much anecdotal use of the research peptides BPC-157 and TB500 for musculoskeletal issues. Although these compounds are outside the scope of what a physician can prescribe, what's your opinion, if any, on these compounds and what has been your observation with patients using them? 3) I am 57, not on TRT, and produce a total T between the mid 400s-mid 600s, while free T is on the low end of normal, depending on time of draw. Libido seems ok. Have increased joint pain and inflammation lately, but don't know if that's related to T levels. If I did wish to further optimize my levels, would you recommend I try a SERM like clomiphene before 'throwing in the towel' and going with TRT as I would prefer to preserve what endogenous T I have left? [/QUOTE]
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