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<blockquote data-quote="Rand McClain DO" data-source="post: 88237" data-attributes="member: 90"><p>My supplements change depending upon my goals, time of year, activities, stress levels and other variables. I can say that in my experience, everyone needs supplemental B vitamins and vitamin D3. Remember the Kreb (Citric Acid) Cycle? Need B vitamins, magnesium, zinc and coenzyme Q10 to convert food into usable energy. No one gets enough vitamin (actually steroid hormone) D3 anymore even if they work mostly outdoors. Vitamin D3 is manufactured by the body via liver and kidneys and exposure of skin to sun. No one should get all their vitamin D3 from the sun these days anyway since malignant melanoma is a very real threat now that life expectancy is no longer 28 years as it was just 300 years ago.</p><p>Regarding magnesium intake, I see magnesium, RBC assays that are frequently on the very low side of “normal” (“normal” typically being nowhere near optimum). Magnesium helps relax the smooth muscles of the vasculature and tends to help patients relax in general while improving blood flow to muscles. Again, magnesium is also needed for the Kreb Cycle.</p><p>Magnesium glycinate is well absorbed and I use Designs For Health brand which come in 300 mg capsules. I recommend taking as much as you can tolerate without suffering from any excessive laxative effects (remember that poorly absorbed magnesium like magnesium oxide, hydroxide or sulfite is used for laxative effects). </p><p>Regarding E2 levels, some men do better with higher E2, especially if sensitive to E2. Over suppressed E2 can lead to genital insensitivity, joint pain, low libido and erectile dysfunction and excess E2 can lead to water and fat retention, moodiness and irascibility, erectile dysfunction and libido issues. </p><p>Some of my strength athletes do better with E2 closer to 30-35 pg/mL stating they feel stronger and have fewer joint and tendon issues.</p><p>These days, so much information is available that if you aren’t lazy, you can learn anything. The trick is discerning between good information and bad. That typically takes some formal education and/or experience but I suppose is not necessarily required.</p><p>Stem cells and CRISPR technology are two of the most exciting edges of medicine today. Between the two, we should be able to eventually cure many diseases, reverse most degeneration, and heal much traumatic injury. Quality of life improvement as well as life extension will both be one day as ubiquitous as antibiotics are for bacterial infections. I have seen incredible results with stem cells with finger tips being regrown, symptoms of MS reversed and bucket handle meniscus tears completely healed. Beware the “centers” that offer a few million cells for ridiculous prices. Know the type of cell and source being offered and find doctors who haven’t just jumped on the stem cell bandwagon is my advice.</p></blockquote><p></p>
[QUOTE="Rand McClain DO, post: 88237, member: 90"] My supplements change depending upon my goals, time of year, activities, stress levels and other variables. I can say that in my experience, everyone needs supplemental B vitamins and vitamin D3. Remember the Kreb (Citric Acid) Cycle? Need B vitamins, magnesium, zinc and coenzyme Q10 to convert food into usable energy. No one gets enough vitamin (actually steroid hormone) D3 anymore even if they work mostly outdoors. Vitamin D3 is manufactured by the body via liver and kidneys and exposure of skin to sun. No one should get all their vitamin D3 from the sun these days anyway since malignant melanoma is a very real threat now that life expectancy is no longer 28 years as it was just 300 years ago. Regarding magnesium intake, I see magnesium, RBC assays that are frequently on the very low side of “normal” (“normal” typically being nowhere near optimum). Magnesium helps relax the smooth muscles of the vasculature and tends to help patients relax in general while improving blood flow to muscles. Again, magnesium is also needed for the Kreb Cycle. Magnesium glycinate is well absorbed and I use Designs For Health brand which come in 300 mg capsules. I recommend taking as much as you can tolerate without suffering from any excessive laxative effects (remember that poorly absorbed magnesium like magnesium oxide, hydroxide or sulfite is used for laxative effects). Regarding E2 levels, some men do better with higher E2, especially if sensitive to E2. Over suppressed E2 can lead to genital insensitivity, joint pain, low libido and erectile dysfunction and excess E2 can lead to water and fat retention, moodiness and irascibility, erectile dysfunction and libido issues. Some of my strength athletes do better with E2 closer to 30-35 pg/mL stating they feel stronger and have fewer joint and tendon issues. These days, so much information is available that if you aren’t lazy, you can learn anything. The trick is discerning between good information and bad. That typically takes some formal education and/or experience but I suppose is not necessarily required. Stem cells and CRISPR technology are two of the most exciting edges of medicine today. Between the two, we should be able to eventually cure many diseases, reverse most degeneration, and heal much traumatic injury. Quality of life improvement as well as life extension will both be one day as ubiquitous as antibiotics are for bacterial infections. I have seen incredible results with stem cells with finger tips being regrown, symptoms of MS reversed and bucket handle meniscus tears completely healed. Beware the “centers” that offer a few million cells for ridiculous prices. Know the type of cell and source being offered and find doctors who haven’t just jumped on the stem cell bandwagon is my advice. [/QUOTE]
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