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<blockquote data-quote="Pursuit_Sanus" data-source="post: 124707" data-attributes="member: 13150"><p>Hello Dr. McClain,</p><p></p><p>Appreciate your time and knowledge you spend to answer questions on the forums. I recently had a 23&me dna test done and found I have a lower expression of MAO-A gene (oxidizes serotonin, dopamine, epinephrine, norepinephrine). I've been on TRT for a little over two years and have struggled to get things balanced out. I feel like most of the time has been spent chasing unwanted side effects. Mood swings and acne initially. CBD seemed to clear the acne. HCG always left me feeling a little unbalanced although it did give a libido and sensitivity boost. If I stay off the HCG, my testicles ache almost constantly. I was told recently this lower expression of MAO-A gene can make getting things dialed in quite tricky as this makes me more sensitive to androgens and estrogens. Do you have any experience with this or read up any on how genes can affect this?</p></blockquote><p></p>
[QUOTE="Pursuit_Sanus, post: 124707, member: 13150"] Hello Dr. McClain, Appreciate your time and knowledge you spend to answer questions on the forums. I recently had a 23&me dna test done and found I have a lower expression of MAO-A gene (oxidizes serotonin, dopamine, epinephrine, norepinephrine). I've been on TRT for a little over two years and have struggled to get things balanced out. I feel like most of the time has been spent chasing unwanted side effects. Mood swings and acne initially. CBD seemed to clear the acne. HCG always left me feeling a little unbalanced although it did give a libido and sensitivity boost. If I stay off the HCG, my testicles ache almost constantly. I was told recently this lower expression of MAO-A gene can make getting things dialed in quite tricky as this makes me more sensitive to androgens and estrogens. Do you have any experience with this or read up any on how genes can affect this? [/QUOTE]
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