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Hi Fernando,

Thank you and thank Nelson for this! And, for the videos, the credit goes to Dave "Mad Max" Bourlet (btw, we are now on Jay Cutler's channel/website) For my part, I am more than happy to help if I can.

I do not see how an AI would lead to osteoporosis in a typical male. If one were not replacing or have enough T then, even then, I find it hard to see how an AI might contribute to osteoporosis because one would already have low T and by extension low E, so an AI would either not be reducing E by much or boosting T by blocking its conversion to E. If a male has enough T and is doing just about anything that is weight bearing, he should be preventing osteoporosis. Doctors tend to focus on estrogen, particularly with women, when treating or discussing osteoporosis, but T helps prevent it as well.


TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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