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<blockquote data-quote="ERO" data-source="post: 79766" data-attributes="member: 1210"><p>Hello Dr Ullis-</p><p></p><p>I went through puberty at a normal age and I found out about my low SHBG when I first started experiencing low T symptoms at around age 48 and beginning TRT - and feeling literally nothing from TRT treatment. More research in my part showed that guys with low SHBG often "under respond" to TRT (Just for fun, sometime Google "Low SHBG TRT" and see how many hits you get...)and that has been my experience in the extreme. Even though I am not obese or diabetic, I tried Metformin for a couple of years but it did nothing for me. My glucose levels were fine before starting so they did not change much at all with the Metformin. I have never had a liver scan, but my liver enzymes always come back well within the normal levels. </p><p></p><p>I am intrigued by your idea of doing a trial of moving toward hyperthyroidism for 6 weeks to see if my SHBG levels change. I am willing to try anything at this point and I thank you for the suggestion!</p></blockquote><p></p>
[QUOTE="ERO, post: 79766, member: 1210"] Hello Dr Ullis- I went through puberty at a normal age and I found out about my low SHBG when I first started experiencing low T symptoms at around age 48 and beginning TRT - and feeling literally nothing from TRT treatment. More research in my part showed that guys with low SHBG often "under respond" to TRT (Just for fun, sometime Google "Low SHBG TRT" and see how many hits you get...)and that has been my experience in the extreme. Even though I am not obese or diabetic, I tried Metformin for a couple of years but it did nothing for me. My glucose levels were fine before starting so they did not change much at all with the Metformin. I have never had a liver scan, but my liver enzymes always come back well within the normal levels. I am intrigued by your idea of doing a trial of moving toward hyperthyroidism for 6 weeks to see if my SHBG levels change. I am willing to try anything at this point and I thank you for the suggestion! [/QUOTE]
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