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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Arimidex - Pain Caused by Crashing E2 or Another Reason?
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<blockquote data-quote="PhantomFear" data-source="post: 179929" data-attributes="member: 38928"><p>I appreciate your points, and I understand the limitations of those studies. I wasn't trying to claim that arimidex is dropping guys progesterone levels in half. I was suggesting that the side effect's associated with low doses - which are attributed to a reduction in estrogen, despite serum estrogen remains relatively unchanged, and often remaining high - are more likely a product of reduced progesterone and the expression of it's receptor.</p><p></p><p>If 1mg a day is causing a ~50% drop in progesterone receptor expression, you don't think 1mg a week is going to have any effect on prog at all? My point isn't that it's going to drop absolute serum levels by a large margin; more that any drop, even if small, is going to have a large impact on a man if they are already deficient in prog - as is the case for most men on TRT.</p><p></p><p>Out of curiosity, what dose of prog are you using? I never claimed it was a miracle cure, because I don't think any exogenous hormone is. I've taken it myself on TRT and got okay-ish results, but nothing that impressive. I found pregnenolone a much better option than progesterone whilst on T.</p><p></p><p>The < 0.141 nmol/L reading on TRT was run by the exact same lab that produced the 1.4 nmol/L reading only four weeks apart. I've never seen a man not test > 0.141 nmol/L when using the same lab - even those on TRT.</p><p></p><p>Saya noticed the same thing when the lab ranges first got changed. You can read his comments <a href="https://www.excelmale.com/forum/threads/new-labs-progesterone-high.8623/#post-53267" target="_blank">here.</a></p></blockquote><p></p>
[QUOTE="PhantomFear, post: 179929, member: 38928"] I appreciate your points, and I understand the limitations of those studies. I wasn't trying to claim that arimidex is dropping guys progesterone levels in half. I was suggesting that the side effect's associated with low doses - which are attributed to a reduction in estrogen, despite serum estrogen remains relatively unchanged, and often remaining high - are more likely a product of reduced progesterone and the expression of it's receptor. If 1mg a day is causing a ~50% drop in progesterone receptor expression, you don't think 1mg a week is going to have any effect on prog at all? My point isn't that it's going to drop absolute serum levels by a large margin; more that any drop, even if small, is going to have a large impact on a man if they are already deficient in prog - as is the case for most men on TRT. Out of curiosity, what dose of prog are you using? I never claimed it was a miracle cure, because I don't think any exogenous hormone is. I've taken it myself on TRT and got okay-ish results, but nothing that impressive. I found pregnenolone a much better option than progesterone whilst on T. The < 0.141 nmol/L reading on TRT was run by the exact same lab that produced the 1.4 nmol/L reading only four weeks apart. I've never seen a man not test > 0.141 nmol/L when using the same lab - even those on TRT. Saya noticed the same thing when the lab ranges first got changed. You can read his comments [URL='https://www.excelmale.com/forum/threads/new-labs-progesterone-high.8623/#post-53267']here.[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Arimidex - Pain Caused by Crashing E2 or Another Reason?
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