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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Arimidex - Pain Caused by Crashing E2 or Another Reason?
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<blockquote data-quote="TLawyer" data-source="post: 178958" data-attributes="member: 40115"><p>I believe that I've seen a thread that one 1mg dose of Arimidex decreases E2 by about 70% within 24 hours, and then up to 80% when taken on regular basis thereafter. Are we able to extrapolate from that how much a single .25mg does would decrease E2? Would it be about 17.5%?</p><p></p><p>I asked because after staying of Arimidex for about 2 weeks or so, I took at .25mg dose to see whether I felt any difference. And I definitely did within about 7 hours and still am about 36 hours after that dose. Libido and sensitivity definitely improved in that 7 hours, and I feel like erection strength as well. I am low SHBG (11 at my last lab test using this protocol), and my last E2 level came in at about 55 on my current protocol (probably was higher before I took the Arimidex as I registered that 55 about 3 and half days after taking a .125 mg dose, and then stopped taking it to see how I felt, so I imagine it rose during those 2 weeks). Mentally felt better as well, although that may go along with a better libido and sensitivity. I am amazed as how quickly I felt a difference. If it is about a 17.5% decrease in E2, that would put me on the low end of about 45 (17.5% of 55). I'm just trying to get a sense of a good level for me with my E2 given that I can't run out to a lab until Tuesday, so I can't get a confirmed level (and who knows how I will feel on Tuesday). That 45 still seems like it may be on the higher end, so my thought is that perhaps .25mg is decreasing it more than 17.5%.</p><p></p><p>I will say that the only drawback is that I woke up with morning (about 24 hours after I took the .25mg dose) with my joints killing me and elbow pain, which I have suffered with since starting the smaller doses of Arimidex about 2 months ago. Physically, as far as pain, I have gradually felt better after stopping the Arimidex for those 2 weeks, including the elbow pain, but it's definitely back today after taking a dose. I had originally thought when I was experiencing that pain that I was crashing my E2, but then I came back with the 55 level, so that clearly wasn't the case. I looked up Arimidex, and I see that joint and muscle pain is a common side effect. My question is this - is that because people are crashing their E2 with Arimidex, or is it for another reason (i.e. you can experience the pain even if you don't crash E2)? Because I am not crashing it, but I definitely feel the pain almost immediately.</p><p></p><p>The pain is a little disappointing, although the libido and sensitivity increase certainly have overshadowed it.</p></blockquote><p></p>
[QUOTE="TLawyer, post: 178958, member: 40115"] I believe that I've seen a thread that one 1mg dose of Arimidex decreases E2 by about 70% within 24 hours, and then up to 80% when taken on regular basis thereafter. Are we able to extrapolate from that how much a single .25mg does would decrease E2? Would it be about 17.5%? I asked because after staying of Arimidex for about 2 weeks or so, I took at .25mg dose to see whether I felt any difference. And I definitely did within about 7 hours and still am about 36 hours after that dose. Libido and sensitivity definitely improved in that 7 hours, and I feel like erection strength as well. I am low SHBG (11 at my last lab test using this protocol), and my last E2 level came in at about 55 on my current protocol (probably was higher before I took the Arimidex as I registered that 55 about 3 and half days after taking a .125 mg dose, and then stopped taking it to see how I felt, so I imagine it rose during those 2 weeks). Mentally felt better as well, although that may go along with a better libido and sensitivity. I am amazed as how quickly I felt a difference. If it is about a 17.5% decrease in E2, that would put me on the low end of about 45 (17.5% of 55). I'm just trying to get a sense of a good level for me with my E2 given that I can't run out to a lab until Tuesday, so I can't get a confirmed level (and who knows how I will feel on Tuesday). That 45 still seems like it may be on the higher end, so my thought is that perhaps .25mg is decreasing it more than 17.5%. I will say that the only drawback is that I woke up with morning (about 24 hours after I took the .25mg dose) with my joints killing me and elbow pain, which I have suffered with since starting the smaller doses of Arimidex about 2 months ago. Physically, as far as pain, I have gradually felt better after stopping the Arimidex for those 2 weeks, including the elbow pain, but it's definitely back today after taking a dose. I had originally thought when I was experiencing that pain that I was crashing my E2, but then I came back with the 55 level, so that clearly wasn't the case. I looked up Arimidex, and I see that joint and muscle pain is a common side effect. My question is this - is that because people are crashing their E2 with Arimidex, or is it for another reason (i.e. you can experience the pain even if you don't crash E2)? Because I am not crashing it, but I definitely feel the pain almost immediately. The pain is a little disappointing, although the libido and sensitivity increase certainly have overshadowed it. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
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Arimidex - Pain Caused by Crashing E2 or Another Reason?
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