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Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
Are guys that do well on low dose clomid unicorns...or do they really exist?
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<blockquote data-quote="Dr Justin Saya MD" data-source="post: 31908" data-attributes="member: 12687"><p>You caught me just before going offline ;-) I'll take a quick stab at your question. I love educating if you haven't suspected already!</p><p></p><p>So...there really isn't a better way to manage the estrogenic effects of the zuclomiphene other than simply LIMITING the burden of zuclomiphene (via dosage adjustment of Clomid) based on the patient's sensitivity. This is superior to DIM, CDG, or AI. Now some patients tolerate the zuclomiphene fine even at higher Clomid dosages, some need much lower due to sensitivity...this is where working with an experienced practitioner is IMPERATIVE! </p><p></p><p>Also keep in mind that with the increase in testosterone with SUCCESSFUL Clomid treatment -> there will be a concurrent increase in E2. Now this is cumulative to the estrogenic zuclomiphene effect (thus an E2 level of 30pg/mL in a TRT guy isn't apples to apples comparable to an E2 level of 30pg/mL in a Clomid guy).. Hope that makes sense as that is a difficult concept for even most physicians that treat with Clomid (and not coincidentally a common reason for the failure of their Clomid treatment for their patients). Now that increase in endogenous E2 (again concurrent with the estrogenic zuclomiphene), IF CAUSING ISSUES - will respond to DIM, CDG, and if needed LOW dose anastrozole (with AI > DIM/CDG). </p><p></p><p>Hope this makes sense, even many physicians I try to educate on this cannot grasp it!</p></blockquote><p></p>
[QUOTE="Dr Justin Saya MD, post: 31908, member: 12687"] You caught me just before going offline ;-) I'll take a quick stab at your question. I love educating if you haven't suspected already! So...there really isn't a better way to manage the estrogenic effects of the zuclomiphene other than simply LIMITING the burden of zuclomiphene (via dosage adjustment of Clomid) based on the patient's sensitivity. This is superior to DIM, CDG, or AI. Now some patients tolerate the zuclomiphene fine even at higher Clomid dosages, some need much lower due to sensitivity...this is where working with an experienced practitioner is IMPERATIVE! Also keep in mind that with the increase in testosterone with SUCCESSFUL Clomid treatment -> there will be a concurrent increase in E2. Now this is cumulative to the estrogenic zuclomiphene effect (thus an E2 level of 30pg/mL in a TRT guy isn't apples to apples comparable to an E2 level of 30pg/mL in a Clomid guy).. Hope that makes sense as that is a difficult concept for even most physicians that treat with Clomid (and not coincidentally a common reason for the failure of their Clomid treatment for their patients). Now that increase in endogenous E2 (again concurrent with the estrogenic zuclomiphene), IF CAUSING ISSUES - will respond to DIM, CDG, and if needed LOW dose anastrozole (with AI > DIM/CDG). Hope this makes sense, even many physicians I try to educate on this cannot grasp it! [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
Are guys that do well on low dose clomid unicorns...or do they really exist?
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