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The MAIN benefit of low dose Clomid (which is really anything 25mg or less) is exactly that - to minimize the estrogenic impact of the zuclomiphene. Also less SHBG stimulation at lower doses (although that SHBG stimulation can actually be a GOOD thing for low SHBG guys).


I like DIM at 100mg daily or 200mg BIW-TIW (I often add this to compounded low dose anastrozole WHEN the AI is needed). Calcium D-Glucarate can help typically at doses of 1000-1500mg daily. However, for guys that have true E2 sensitivity/symptoms, neither of these will have the efficacy of a LOW dose of anastrozole.


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