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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Are E2 Tests Useless??
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<blockquote data-quote="JRos895" data-source="post: 230057" data-attributes="member: 43163"><p>This intracrine approach to E2 and serum testing is totally misleading and I don’t think Danny Bossa has any clue what he’s talking about. I read a Reddit post where he was arguing with a pro AI poster and Danny said “E2 is an intracrine hormone—look up what that means and tell me why AIs should be used”. He was clearly trying to shift the burden of proof because he doesn’t know what “intracrine” is.</p><p></p><p>Yes, E2 is an “intracrine hormone” but so are almost all steroid hormones in the body, testosterone included. If it was useless to measure E2, it would also be useless to measure testosterone or progesterone.</p><p></p><p>The serum levels are still helpful to know because the serum levels are like the highway for hormones. If the highway is jammed with traffic, there is a very strong chance the freeways and local roads will have strong traffic too.</p><p></p><p>Finasteride for example reduces serum DHT levels by 61%, but reduces hair follicle DHT levels by 65%, so a very close reduction. So just because DHT has intracrine action does not mean that it’s not helpful to know serum levels.</p></blockquote><p></p>
[QUOTE="JRos895, post: 230057, member: 43163"] This intracrine approach to E2 and serum testing is totally misleading and I don’t think Danny Bossa has any clue what he’s talking about. I read a Reddit post where he was arguing with a pro AI poster and Danny said “E2 is an intracrine hormone—look up what that means and tell me why AIs should be used”. He was clearly trying to shift the burden of proof because he doesn’t know what “intracrine” is. Yes, E2 is an “intracrine hormone” but so are almost all steroid hormones in the body, testosterone included. If it was useless to measure E2, it would also be useless to measure testosterone or progesterone. The serum levels are still helpful to know because the serum levels are like the highway for hormones. If the highway is jammed with traffic, there is a very strong chance the freeways and local roads will have strong traffic too. Finasteride for example reduces serum DHT levels by 61%, but reduces hair follicle DHT levels by 65%, so a very close reduction. So just because DHT has intracrine action does not mean that it’s not helpful to know serum levels. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Are E2 Tests Useless??
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