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In conclusion, dietary supplementation with 1.5 g/day ARA for 4 wk resulted in greater acute inflammatory responses to an acute bout of resistance exercise in previously trained young healthy men. The effects of ARA on exercise-induced inflammation were transient, however, and had fully resolved within 48 h. There was also no evidence that the increased inflammatory response to exercise stress in men receiving dietary ARA supplementation impeded recovery of muscle force or increased symptoms of muscle soreness. These data show for the first time that dietary ARA intake can transiently modulate immune cell responses in human participants in vivo but that exposure to an acute inflammatory stimulus, such as exercise induced muscle damage, is required to reveal this effect.