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Peptide Forums (GHRH, Sermorelin, etc)
General Peptide Use & Information
Anyone using Rapamycin for anti-aging?
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<blockquote data-quote="Guided_by_Voices" data-source="post: 212144" data-attributes="member: 15235"><p>A very big topic, but a few comments...my lab rat has been using it at a dose of 4-5mg every other week for the past two years. There appear to be no downsides at all, however upsides are hard to identify exactly when one is doing many other things as well. A few observations...it appears to work by both the mtor affect and the senolytic affect. In intermittent amounts it seems to have no athletic downside at all and may actually be of benefit. It also apparently boosts immune function and is likely anti-cancer. Trials in dogs have been positive so far and there is a lengthy podcast on Peter Attia's site from several months ago that goes into it in great detail. The other modalities mentioned above should reduce the rate of aging however Rapamycin is the only compound I can think of that actually appears to reverse aging. IMO it is a must-take as there are no (NO!) downsides I have heard of for small intermittent doses and potentially large benefits. All of us over 40 have to make decisions based on imperfect information and even if a quality study was attempted in humans (unlikely) it would be a long time if ever before we would have a definitive answer.</p><p></p><p>Regarding HGH, another big topic, but I think it is unfairly maligned and has much untapped potential, especially for injury recovery and general robustness. The arguments against it do not necessarily apply in real world situations for otherwise healthy adults who do not have chronically elevated insulin. I have not used it although I have used several peptides which promote HGH secretion. I would start with Rapamycin but if I had a major injury I would not hesitate to give HGH a try. </p><p></p><p>A good place to dive into anti-aging is Josh Mittledorf's blog Aging Matters. The comments are often excellent there too.</p></blockquote><p></p>
[QUOTE="Guided_by_Voices, post: 212144, member: 15235"] A very big topic, but a few comments...my lab rat has been using it at a dose of 4-5mg every other week for the past two years. There appear to be no downsides at all, however upsides are hard to identify exactly when one is doing many other things as well. A few observations...it appears to work by both the mtor affect and the senolytic affect. In intermittent amounts it seems to have no athletic downside at all and may actually be of benefit. It also apparently boosts immune function and is likely anti-cancer. Trials in dogs have been positive so far and there is a lengthy podcast on Peter Attia's site from several months ago that goes into it in great detail. The other modalities mentioned above should reduce the rate of aging however Rapamycin is the only compound I can think of that actually appears to reverse aging. IMO it is a must-take as there are no (NO!) downsides I have heard of for small intermittent doses and potentially large benefits. All of us over 40 have to make decisions based on imperfect information and even if a quality study was attempted in humans (unlikely) it would be a long time if ever before we would have a definitive answer. Regarding HGH, another big topic, but I think it is unfairly maligned and has much untapped potential, especially for injury recovery and general robustness. The arguments against it do not necessarily apply in real world situations for otherwise healthy adults who do not have chronically elevated insulin. I have not used it although I have used several peptides which promote HGH secretion. I would start with Rapamycin but if I had a major injury I would not hesitate to give HGH a try. A good place to dive into anti-aging is Josh Mittledorf's blog Aging Matters. The comments are often excellent there too. [/QUOTE]
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Peptide Forums (GHRH, Sermorelin, etc)
General Peptide Use & Information
Anyone using Rapamycin for anti-aging?
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