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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Anyone tried testosterone base (no ester)?
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<blockquote data-quote="Cataceous" data-source="post: 184431" data-attributes="member: 38109"><p>You want to keep it low enough that peak serum testosterone remains physiological. I'm guessing each dose should be in the range of half a milligram to a few milligrams. With Natesto the doses are nominally 11 mg each, but so far I haven't seen estimates of absorption efficiency. They use three doses a day. In the Natesto trials they are bumping up serum testosterone from 200-300 ng/dL to 750-800.</p><p></p><p>The authors of the Natesto study say that endogenous production is suppressed for a period after each dose, but the relatively long periods between doses allow for continued normal HPTA operation:</p><p><img src="https://www.excelmale.com/forum/attachments/screenshot-705-png.8503/" class="bbImage" alt="" data-url="https://www.excelmale.com/forum/attachments/screenshot-705-png.8503/" style="" /></p><p></p><p>The tricky part with experimenting is getting useful data without having to spend a lot on blood tests and be poked a lot as well. The bare minimum might be to measure serum testosterone one or two hours post-injection, hoping to be near the peak, and then a few hours later to make sure it's coming down fast.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 184431, member: 38109"] You want to keep it low enough that peak serum testosterone remains physiological. I'm guessing each dose should be in the range of half a milligram to a few milligrams. With Natesto the doses are nominally 11 mg each, but so far I haven't seen estimates of absorption efficiency. They use three doses a day. In the Natesto trials they are bumping up serum testosterone from 200-300 ng/dL to 750-800. The authors of the Natesto study say that endogenous production is suppressed for a period after each dose, but the relatively long periods between doses allow for continued normal HPTA operation: [IMG]https://www.excelmale.com/forum/attachments/screenshot-705-png.8503/[/IMG] The tricky part with experimenting is getting useful data without having to spend a lot on blood tests and be poked a lot as well. The bare minimum might be to measure serum testosterone one or two hours post-injection, hoping to be near the peak, and then a few hours later to make sure it's coming down fast. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Anyone tried testosterone base (no ester)?
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