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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Anyone feels better on less frequent injections? for ex.: e7d vs e3.5d
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<blockquote data-quote="madman" data-source="post: 199829" data-attributes="member: 13851"><p>Every time you tweak a protocol whether increasing/decreasing dose hormones will be in flux during the weeks leading up until blood levels stabilize (4-6 weeks when using enanthate/cypionate ester).</p><p></p><p>No way your body has fully adapted during this transition let alone getting dialed in.</p><p></p><p>Most doctors in the know would wait 12 weeks after starting a protocol or tweaking a protocol (dose T/injection frequency).</p><p></p><p>When blood work is done 6 weeks in we want to know how one reacts to T dose and where said protocol (dose T/injection frequency) has trough TT/FT/e2 levels let alone other blood markers as T levels may be too high or too low.</p><p></p><p>Of course, how one feels is critical but the first 6 weeks is misleading and is in no way going to dictate how you will truly feel 2 months after the stabilization period (hormones are in flux) as the body needs time to fully adapt to the new levels.</p><p></p><p>If T levels are healthy at 6 weeks in and one feels descent then you would need to give it a few months to truly gauge how you feel overall regarding relief/improvement of low-T symptoms.</p><p></p><p>If T levels are too low resulting in a lack of any improvement then the dose of T would need to be increased.</p><p></p><p>If T levels are too high resulting in one feeling unwell/experiencing sides then the dose of T would be lowered.</p><p></p><p>Some may even try using ancillaries to control the sides and still run higher T levels.</p><p></p><p>Sure during the first 6 weeks of starting trt let alone tweaking a protocol, it is common for many during this transition to experience what we call the <u><em><strong>honeymoon period where there may be a strong increase in libido/erections and overall euphoric feeling due to increasing T levels/dopamine</strong></em></u><strong><em>.</em></strong></p><p></p><p>Unfortunately, this is temporary and short-lived for most as the body will eventually adjust.</p><p></p><p><strong><u>It is also very common for many men to experience ups/downs in energy/mood/libido/erections/recovery </u><em><u><strong>dur</strong>ing the transition (4-6 weeks) as the body is trying to adjust which can be very misleading</u>.</em></strong></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p>Read this over and over until it sinks in your dome.</p><p></p><p>Even when on trt and tweaking a protocol whether increasing or decreasing T dose hormones will be in flux during the weeks leading up until blood levels have stabilized (4-6 weeks when using enanthate/cypionate ester) and the body will need time to fully adapt.....at least another 2 months after levels have stabilized to truly gauge whether the protocol is a success or failure.</p><p></p><p></p><p><strong>26.What is a reasonable timeline to begin to observe improvements in the signs and symptoms of testosterone deficiency?</strong></p><p><strong></strong></p><p><strong><em>*Following the initiation of testosterone therapy, serum concentrations of testosterone are known to correct earlier than the symptomatic, structural, and metabolic signs associated with TD.76,77</em></strong></p><p><strong><em></em></strong></p><p><strong><em>*As such, patients should be counseled that symptom response will not be immediate. Expectations for treatment response should be established with each patient. Patients can anticipate improvements in many of the common symptoms of TD (libido, energy levels, sexual function) after 3 months of treatment or longer. Metabolic and structural (body composition, muscle mass, bone density) changes may take upwards of 6-months. 77 </em></strong>In addition, patients should be counseled that diet and exercise in combination with testosterone therapy are recommended for body composition changes.</p><p></p><p><strong><em>*Appreciating this pattern of response to testosterone therapy is fundamental when determining the impact of treatment and the appropriate timing of follow-up evaluations while on therapy.</em></strong></p><p><strong><em></em></strong></p><p><strong><em>*For example, if patients undergo a symptom review and measurement of testosterone levels too early (< 3 months), it may lead both physicians and patients to conclude that the treatment has not been impactful (i.e. normal levels of testosterone without symptomatic/structural/metabolic benefit). However, if the same assessment was scheduled 3-6 months after the initiation of therapy, the clinical response tends to be more reflective of normalized levels of serum testosterone.</em></strong></p></blockquote><p></p>
[QUOTE="madman, post: 199829, member: 13851"] Every time you tweak a protocol whether increasing/decreasing dose hormones will be in flux during the weeks leading up until blood levels stabilize (4-6 weeks when using enanthate/cypionate ester). No way your body has fully adapted during this transition let alone getting dialed in. Most doctors in the know would wait 12 weeks after starting a protocol or tweaking a protocol (dose T/injection frequency). When blood work is done 6 weeks in we want to know how one reacts to T dose and where said protocol (dose T/injection frequency) has trough TT/FT/e2 levels let alone other blood markers as T levels may be too high or too low. Of course, how one feels is critical but the first 6 weeks is misleading and is in no way going to dictate how you will truly feel 2 months after the stabilization period (hormones are in flux) as the body needs time to fully adapt to the new levels. If T levels are healthy at 6 weeks in and one feels descent then you would need to give it a few months to truly gauge how you feel overall regarding relief/improvement of low-T symptoms. If T levels are too low resulting in a lack of any improvement then the dose of T would need to be increased. If T levels are too high resulting in one feeling unwell/experiencing sides then the dose of T would be lowered. Some may even try using ancillaries to control the sides and still run higher T levels. Sure during the first 6 weeks of starting trt let alone tweaking a protocol, it is common for many during this transition to experience what we call the [U][I][B]honeymoon period where there may be a strong increase in libido/erections and overall euphoric feeling due to increasing T levels/dopamine[/B][/I][/U][B][I].[/I][/B] Unfortunately, this is temporary and short-lived for most as the body will eventually adjust. [B][U]It is also very common for many men to experience ups/downs in energy/mood/libido/erections/recovery [/U][I][U][B]dur[/B]ing the transition (4-6 weeks) as the body is trying to adjust which can be very misleading[/U].[/I][/B] Read this over and over until it sinks in your dome. Even when on trt and tweaking a protocol whether increasing or decreasing T dose hormones will be in flux during the weeks leading up until blood levels have stabilized (4-6 weeks when using enanthate/cypionate ester) and the body will need time to fully adapt.....at least another 2 months after levels have stabilized to truly gauge whether the protocol is a success or failure. [B]26.What is a reasonable timeline to begin to observe improvements in the signs and symptoms of testosterone deficiency? [I]*Following the initiation of testosterone therapy, serum concentrations of testosterone are known to correct earlier than the symptomatic, structural, and metabolic signs associated with TD.76,77 *As such, patients should be counseled that symptom response will not be immediate. Expectations for treatment response should be established with each patient. Patients can anticipate improvements in many of the common symptoms of TD (libido, energy levels, sexual function) after 3 months of treatment or longer. Metabolic and structural (body composition, muscle mass, bone density) changes may take upwards of 6-months. 77 [/I][/B]In addition, patients should be counseled that diet and exercise in combination with testosterone therapy are recommended for body composition changes. [B][I]*Appreciating this pattern of response to testosterone therapy is fundamental when determining the impact of treatment and the appropriate timing of follow-up evaluations while on therapy. *For example, if patients undergo a symptom review and measurement of testosterone levels too early (< 3 months), it may lead both physicians and patients to conclude that the treatment has not been impactful (i.e. normal levels of testosterone without symptomatic/structural/metabolic benefit). However, if the same assessment was scheduled 3-6 months after the initiation of therapy, the clinical response tends to be more reflective of normalized levels of serum testosterone.[/I][/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Anyone feels better on less frequent injections? for ex.: e7d vs e3.5d
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