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You're neglecting the angle of inducing organ failure and atrophy and that shrunken nuts are not only painful for many men, also make you look like an 8 year old boy. There are a great many things going on here the least of which is pregnenolone or hormonal paths. Or even fertility, if that matters. I'm one I don't care for it, but for all these reasons, I use it. As far as complicating E2, from someone that agrees HCG complicates(ed) my E2...you're using too much at one-time. IMHO. All you need is just enough to keep your testes alive, any more than that, it aromatizes in the testes and controlling that aromatization is more difficult in the testicular environment, where aromatization is favored more than elsewhere. Supplementing Pregnenolone is wise, but IS NOT a substitute or end-around.