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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Any new discoveries on Low SHBG curse ?
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<blockquote data-quote="Cataceous" data-source="post: 271005" data-attributes="member: 38109"><p>I'm getting the sense that you've tried only mid-range TRT dosing and above. There's still a pretty wide margin between where you started naturally and the results you experienced with mid-range TRT. Is this lack of curiosity because of a notion that dosing under 60 mg TC per week won't do anything? In your shoes I'd want to see what happens with 40 and 50 mg TC/week in divided doses. Would suppression of SHBG be less drastic? </p><p></p><p>Another test would be to use <strong>small</strong> daily doses of testosterone propionate or a propionate/cypionate blend. It's possible that peak daily serum testosterone is more directly related to the benefits of testosterone, while trough and average levels are more the drivers of side effects. While this is speculative, there are some guys here who seem to do better with daily use of a blend than with other protocols.</p><p></p><p>Another idea, and the best one if you're not on TRT at the moment, is to run a trial with testosterone nasal gel. This has much less impact on other hormones, and allows you to experience much higher peak serum testosterone without having large increases in trough or average levels.</p><p></p><p>Have you already been exposed to the ideas about low SHBG quoted <a href="https://www.excelmale.com/forum/threads/low-shbg-means-high-free-e2.24592/#post-214176" target="_blank">here</a>? Unfortunately, even if they are correct they do not point to an easy solution. If SHBG suitable for injection were readily available then it would make experimentation pretty simple. An injection every few days would raise SHBG to any desired level. However, I suspect the cost of synthesis will need to get a lot lower before SHBG becomes affordable for this niche.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 271005, member: 38109"] I'm getting the sense that you've tried only mid-range TRT dosing and above. There's still a pretty wide margin between where you started naturally and the results you experienced with mid-range TRT. Is this lack of curiosity because of a notion that dosing under 60 mg TC per week won't do anything? In your shoes I'd want to see what happens with 40 and 50 mg TC/week in divided doses. Would suppression of SHBG be less drastic? Another test would be to use [B]small[/B] daily doses of testosterone propionate or a propionate/cypionate blend. It's possible that peak daily serum testosterone is more directly related to the benefits of testosterone, while trough and average levels are more the drivers of side effects. While this is speculative, there are some guys here who seem to do better with daily use of a blend than with other protocols. Another idea, and the best one if you're not on TRT at the moment, is to run a trial with testosterone nasal gel. This has much less impact on other hormones, and allows you to experience much higher peak serum testosterone without having large increases in trough or average levels. Have you already been exposed to the ideas about low SHBG quoted [URL='https://www.excelmale.com/forum/threads/low-shbg-means-high-free-e2.24592/#post-214176']here[/URL]? Unfortunately, even if they are correct they do not point to an easy solution. If SHBG suitable for injection were readily available then it would make experimentation pretty simple. An injection every few days would raise SHBG to any desired level. However, I suspect the cost of synthesis will need to get a lot lower before SHBG becomes affordable for this niche. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Any new discoveries on Low SHBG curse ?
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