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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Anxiety and anger on TRT
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<blockquote data-quote="DS3" data-source="post: 181763" data-attributes="member: 18514"><p>So here is some evidence-based, non anecdotal information behind nandrolone.</p><p></p><p>“While testosterone’s 5α-metabolite, dihydrotestosterone (DHT), has a very high affinity for the AR, nandrolone’s 5α-metabolite, 5α-dihydro-19-nortestosterone, has a significantly lower affinity, even lower than nandrolone itself (<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108994/#r17" target="_blank">17</a>). Thus, the conversion of nandrolone to its 5α-metabolite results in a characteristically different AR activation in androgenic tissues when it was compared to testosterone and DHT with specifically preserved AR activation in skeletal muscle.”</p><p></p><p>“Nandrolone has been shown to possess a generally favorable side effect profile compared to most other AAS. Although any androgenic stimulation of the hair follicle and sebaceous sweat glands may result in alopecia, hirsutism, and acne, nandrolone’s weak androgenic activity makes these side effects uncommon (<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108994/#r28" target="_blank">28</a>).”</p><p></p><p></p><p>Pay attention to those key words...nandrolones weak androgenic activity is these tissues makes alopecia uncommon.</p><p></p><p>[URL unfurl="true"]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108994/[/URL]</p><p></p><p>I am a competitive bodybuilder and train competitive bodybuilders. From an anecdotal perspective, I have never seen increased hair loss from adding nandrolone to testosterone. In fact, anecdotally I have seen the opposite.</p></blockquote><p></p>
[QUOTE="DS3, post: 181763, member: 18514"] So here is some evidence-based, non anecdotal information behind nandrolone. “While testosterone’s 5α-metabolite, dihydrotestosterone (DHT), has a very high affinity for the AR, nandrolone’s 5α-metabolite, 5α-dihydro-19-nortestosterone, has a significantly lower affinity, even lower than nandrolone itself ([URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108994/#r17']17[/URL]). Thus, the conversion of nandrolone to its 5α-metabolite results in a characteristically different AR activation in androgenic tissues when it was compared to testosterone and DHT with specifically preserved AR activation in skeletal muscle.” “Nandrolone has been shown to possess a generally favorable side effect profile compared to most other AAS. Although any androgenic stimulation of the hair follicle and sebaceous sweat glands may result in alopecia, hirsutism, and acne, nandrolone’s weak androgenic activity makes these side effects uncommon ([URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108994/#r28']28[/URL]).” Pay attention to those key words...nandrolones weak androgenic activity is these tissues makes alopecia uncommon. [URL unfurl="true"]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108994/[/URL] I am a competitive bodybuilder and train competitive bodybuilders. From an anecdotal perspective, I have never seen increased hair loss from adding nandrolone to testosterone. In fact, anecdotally I have seen the opposite. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Anxiety and anger on TRT
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