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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
anti-depressive/mood enhancing effect of celebrex(?) Alternatives?
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<blockquote data-quote="Aki" data-source="post: 91440" data-attributes="member: 14084"><p>Hi all,</p><p></p><p>I was recently prescribed some Celebrex (celecoxib) for persistent lower back pain. I took it for about two week (200 mg/day) and it provided relief for the back pain symptoms. The last dose was 3 nights ago. During the second week while I was on celebrex, my state of mind (mood, mental energy, non-anxiety and feeling of confidence/positiviteness/optimism) was pretty good - significantly better usual. I didn't associate this phenomenon particularly with the celebrex, as I'm also taking enclomiphene and some anti-histamine for itching problems. Also, vit-D 50000 units 2x/week. And Magnesium. </p><p></p><p>Since stopping celebrex, my mood has taken a downturn, i.e. it's gone back to how it usually is - which isn't good.</p><p>I'm beginning to wonder if Celebrex had anything to do with it (not to rush to conclusions). Googling returned some research about COX-2 inhibitors (celebrex being one) having an anti-depressant effect, in isolation or as add-on therapy to boost the effectiveness of other antideps.</p><p></p><p> <a href="https://www.sciencedaily.com/releases/2016/11/161110145921.htm" target="_blank">https://www.ncbi.nlm.nih.gov/pubmed/20047157</a></p><p><a href="https://www.sciencedaily.com/releases/2016/11/161110145921.htm" target="_blank">https://www.sciencedaily.com/releases/2016/11/161110145921.htm</a></p><p></p><p><strong>I want to know if anyone else has experienced similar effects with celebrex or related medications (naproxen, etc.)?</strong></p><p><strong>Also, could anyone suggest any over-the-counter alternatives (supplements etc.) that could help improve mood?</strong></p><p></p><p>TBH if this (i.e. Celebrex) is what it takes to feel normal, I'm willing to take it indefinitely (long term side-effects notwithstanding). But I would like to explore safer options first.</p><p></p><p>[I should mention that I haven't take antidepressants in years. Back in 2010/2011 I was put on SSRI antidepressants (cymbalta + zoloft). I took them for a bit over a year, after which I gave them up; I don't think they helped me at all (and instead gave me sexual dysfunction-related issues).]</p></blockquote><p></p>
[QUOTE="Aki, post: 91440, member: 14084"] Hi all, I was recently prescribed some Celebrex (celecoxib) for persistent lower back pain. I took it for about two week (200 mg/day) and it provided relief for the back pain symptoms. The last dose was 3 nights ago. During the second week while I was on celebrex, my state of mind (mood, mental energy, non-anxiety and feeling of confidence/positiviteness/optimism) was pretty good - significantly better usual. I didn't associate this phenomenon particularly with the celebrex, as I'm also taking enclomiphene and some anti-histamine for itching problems. Also, vit-D 50000 units 2x/week. And Magnesium. Since stopping celebrex, my mood has taken a downturn, i.e. it's gone back to how it usually is - which isn't good. I'm beginning to wonder if Celebrex had anything to do with it (not to rush to conclusions). Googling returned some research about COX-2 inhibitors (celebrex being one) having an anti-depressant effect, in isolation or as add-on therapy to boost the effectiveness of other antideps. [URL="https://www.sciencedaily.com/releases/2016/11/161110145921.htm"]https://www.ncbi.nlm.nih.gov/pubmed/20047157 https://www.sciencedaily.com/releases/2016/11/161110145921.htm[/URL] [B]I want to know if anyone else has experienced similar effects with celebrex or related medications (naproxen, etc.)? Also, could anyone suggest any over-the-counter alternatives (supplements etc.) that could help improve mood?[/B] TBH if this (i.e. Celebrex) is what it takes to feel normal, I'm willing to take it indefinitely (long term side-effects notwithstanding). But I would like to explore safer options first. [I should mention that I haven't take antidepressants in years. Back in 2010/2011 I was put on SSRI antidepressants (cymbalta + zoloft). I took them for a bit over a year, after which I gave them up; I don't think they helped me at all (and instead gave me sexual dysfunction-related issues).] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
anti-depressive/mood enhancing effect of celebrex(?) Alternatives?
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