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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Another water retention issue
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<blockquote data-quote="madman" data-source="post: 201826" data-attributes="member: 13851"><p>That says it all!</p><p></p><p>You were basically hitting a very high-end trough TT 925 ng/dL (7 days post-injection) and seeing as your SHBG was only 34 nmol/L then it would be a given that your trough FT level would be very high.</p><p></p><p>The shit kicker here is your peak TT/FT let alone estradiol will be much higher 8-24 hrs post-injection/during the first few days of the week.</p><p></p><p>The downfall of injecting larger doses of T once weekly is that not only will there be a significant difference in peak-->trough but blood levels will not be as stable throughout the week which can wreak havoc on one's mood/energy/libido/erections and recovery.</p><p></p><p>Although some men do feel well when injecting once weekly most are splitting up their weekly dose and injecting twice weekly (every 3.5 days) let alone many with low SHBG inject smaller doses of T daily or EOD.</p><p></p><p>SHBG is critical to know as not only will it have a significant impact on FT but can also dictate what injection frequency may suit you best.</p><p></p><p>The benefit of injecting lower doses of T more frequently is that you will be clipping the peak--->trough let alone maintain more stable levels throughout the week.</p><p></p><p>An FT of 5-10 ng/dL would be considered low.</p><p></p><p>FT 16-31 ng/dL is considered healthy.</p><p></p><p>Most men on trt will do well having FT in the 20-30 ng/dL range and some may run slightly higher levels.</p><p></p><p>With a trough TT 925 ng/dL and SHBG 34 nmol/L your FT is most likely over 30 ng/dL and again your peak levels earlier in the week will be <u>much higher</u>.</p><p></p><p>You would most likely do much better starting off on 80 mg/week and splitting the dose into twice-weekly injections (40 mg every 3.5 days).</p><p></p><p>Most men on trt are injecting 100-200 mg/week.</p><p></p><p>Many men would never need the high-end dose of 200 mg/week and can easily achieve a healthy FT level on 100-150 mg/week let alone high or in some cases absurdly high FT on such dose.</p><p></p><p>Believe it or not, some men can achieve high levels on <100 mg/week.</p><p></p><p>Where your TT/SHBG sits is going to play a big role.</p><p></p><p>Unfortunately many are running absurdly high FT levels at a trough well above what would be needed to experience the beneficial effects of trt.</p><p></p><p>Let alone have no clue where their FT level truly sits as they are not testing using the most accurate assays.</p><p></p><p>Too many get caught up in the more T is better mentality.</p><p></p><p>Most commonly prescribed esterified T injections are enanthate or cypionate.</p><p></p><p>When starting trt or tweaking a protocol Increasing/decreasing dose of T) you need to wait 4-6 weeks until blood levels stabilize due to the ester/PK before having blood work done.....testing at the true trough (lowest point) to see where said protocol (dose T/injection frequency) has your TT/FT/estradiol/SHBG and in some cases DHT/prolactin let alone important blood markers such as RBCs/hemoglobin/hematocrit.</p></blockquote><p></p>
[QUOTE="madman, post: 201826, member: 13851"] That says it all! You were basically hitting a very high-end trough TT 925 ng/dL (7 days post-injection) and seeing as your SHBG was only 34 nmol/L then it would be a given that your trough FT level would be very high. The shit kicker here is your peak TT/FT let alone estradiol will be much higher 8-24 hrs post-injection/during the first few days of the week. The downfall of injecting larger doses of T once weekly is that not only will there be a significant difference in peak-->trough but blood levels will not be as stable throughout the week which can wreak havoc on one's mood/energy/libido/erections and recovery. Although some men do feel well when injecting once weekly most are splitting up their weekly dose and injecting twice weekly (every 3.5 days) let alone many with low SHBG inject smaller doses of T daily or EOD. SHBG is critical to know as not only will it have a significant impact on FT but can also dictate what injection frequency may suit you best. The benefit of injecting lower doses of T more frequently is that you will be clipping the peak--->trough let alone maintain more stable levels throughout the week. An FT of 5-10 ng/dL would be considered low. FT 16-31 ng/dL is considered healthy. Most men on trt will do well having FT in the 20-30 ng/dL range and some may run slightly higher levels. With a trough TT 925 ng/dL and SHBG 34 nmol/L your FT is most likely over 30 ng/dL and again your peak levels earlier in the week will be [U]much higher[/U]. You would most likely do much better starting off on 80 mg/week and splitting the dose into twice-weekly injections (40 mg every 3.5 days). Most men on trt are injecting 100-200 mg/week. Many men would never need the high-end dose of 200 mg/week and can easily achieve a healthy FT level on 100-150 mg/week let alone high or in some cases absurdly high FT on such dose. Believe it or not, some men can achieve high levels on <100 mg/week. Where your TT/SHBG sits is going to play a big role. Unfortunately many are running absurdly high FT levels at a trough well above what would be needed to experience the beneficial effects of trt. Let alone have no clue where their FT level truly sits as they are not testing using the most accurate assays. Too many get caught up in the more T is better mentality. Most commonly prescribed esterified T injections are enanthate or cypionate. When starting trt or tweaking a protocol Increasing/decreasing dose of T) you need to wait 4-6 weeks until blood levels stabilize due to the ester/PK before having blood work done.....testing at the true trough (lowest point) to see where said protocol (dose T/injection frequency) has your TT/FT/estradiol/SHBG and in some cases DHT/prolactin let alone important blood markers such as RBCs/hemoglobin/hematocrit. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Another water retention issue
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