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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Another new guy here with questions
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<blockquote data-quote="xqfq" data-source="post: 147468" data-attributes="member: 38167"><p>Hi BillS, welcome to the forum! I'm also new here, and new to TRT. But I've done a lot of research over the past couple of years so hopefully I can be a little helpful.</p><p></p><p></p><p>Clomid:</p><p>--------</p><p></p><p>From what I've read, most guys don't have success with clomid long term. There are outliers who do have success, though. Clomid will boost your total testosterone levels if you're secondary, but often does not provide long-term symptom relief. This may be because clomid, as a SERM, raises SHBG. As a SERM, it also has estrogenic effects in the body and in the brain. Clomid also has two isomers each with their own half life, and the secondary isomer (called Zuclomiphene), is highly estrogenic. So some guys feel good for a little while until the secondary isomer builds up in their system. You can see this graph for some information: [MEDIA=reddit]Testosterone/comments/59ceh2[/MEDIA]</p><p></p><p>There was a trialed drug that contained only the enclomiphene isomer of clomid, but it failed in trials as it didn't improve clinical endpoints the way that testosterone did. But for guys that find some success in clomid, they're likely to find more success in this cancelled drug (IMO). </p><p></p><p>Aveed:</p><p>-------</p><p></p><p>Your doctor probably doesn't know whether or not you'd be comfortable doing 1x-3x / a week injections at home. Aveed makes this a bit easier for the doctor. I have read that there is a risk of a lung issue called pulmonary oil with this product, as the injection is very large.</p><p></p><p>My worry would be that it would be hard to 'dial in' my dosage over the first year on TRT given the long half life of the drug.</p><p></p><p>If you're comfortable doing home injections, you may want to tell the doctor that. He's probably pushing Aveed just because it's easier.</p><p></p><p>General thoughts:</p><p>--------------------</p><p></p><p>At least your doctor wants to treat your testosterone issues! So you've got that going for you. As far as alternatives, there are many specialized testosterone services (e.g. telemedicine, which is what I use), but they have out of pocket costs that may be a consideration.</p></blockquote><p></p>
[QUOTE="xqfq, post: 147468, member: 38167"] Hi BillS, welcome to the forum! I'm also new here, and new to TRT. But I've done a lot of research over the past couple of years so hopefully I can be a little helpful. Clomid: -------- From what I've read, most guys don't have success with clomid long term. There are outliers who do have success, though. Clomid will boost your total testosterone levels if you're secondary, but often does not provide long-term symptom relief. This may be because clomid, as a SERM, raises SHBG. As a SERM, it also has estrogenic effects in the body and in the brain. Clomid also has two isomers each with their own half life, and the secondary isomer (called Zuclomiphene), is highly estrogenic. So some guys feel good for a little while until the secondary isomer builds up in their system. You can see this graph for some information: [MEDIA=reddit]Testosterone/comments/59ceh2[/MEDIA] There was a trialed drug that contained only the enclomiphene isomer of clomid, but it failed in trials as it didn't improve clinical endpoints the way that testosterone did. But for guys that find some success in clomid, they're likely to find more success in this cancelled drug (IMO). Aveed: ------- Your doctor probably doesn't know whether or not you'd be comfortable doing 1x-3x / a week injections at home. Aveed makes this a bit easier for the doctor. I have read that there is a risk of a lung issue called pulmonary oil with this product, as the injection is very large. My worry would be that it would be hard to 'dial in' my dosage over the first year on TRT given the long half life of the drug. If you're comfortable doing home injections, you may want to tell the doctor that. He's probably pushing Aveed just because it's easier. General thoughts: -------------------- At least your doctor wants to treat your testosterone issues! So you've got that going for you. As far as alternatives, there are many specialized testosterone services (e.g. telemedicine, which is what I use), but they have out of pocket costs that may be a consideration. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Another new guy here with questions
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