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So I started taking ZMA for the 50 mgs of zinc it contains in an effort to bring down my borderline high estradiol levels- last two labs showed 34.9 and 36.6 ref 8.0 - 35 sensitive assay. This is the only change in my protocol in the past 6 -8 weeks. Test levels are around 658 and free test 19 from last lab. My libido has declined very noticeably from a subjective standpoint. As I'm not in a sexual relationship it's not an issue other than adding another confounding variable in this game of testosterone management. On the flip side, due to the ZMA, my sleep quality has improved, so maybe it's a wash on the scorecard. But I think I may ditch the zinc since it hasn't helped the estradiol situation. Thoughts, comments?

[QUOTE="DxHypo, post: 21844, member: 6088"] So I started taking ZMA for the 50 mgs of zinc it contains in an effort to bring down my borderline high estradiol levels- last two labs showed 34.9 and 36.6 ref 8.0 - 35 sensitive assay. This is the only change in my protocol in the past 6 -8 weeks. Test levels are around 658 and free test 19 from last lab. My libido has declined very noticeably from a subjective standpoint. As I'm not in a sexual relationship it's not an issue other than adding another confounding variable in this game of testosterone management. On the flip side, due to the ZMA, my sleep quality has improved, so maybe it's a wash on the scorecard. But I think I may ditch the zinc since it hasn't helped the estradiol situation. Thoughts, comments? [/QUOTE]

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TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038