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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
Anavar (Oxandrolone) Blood Levels Increased by Caffeine
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<blockquote data-quote="Nelson Vergel" data-source="post: 17585" data-attributes="member: 3"><p>Mavros Y, O'Neill E, Connerty M, Bean JF, Broe K, et al. <strong></strong></p><p><strong></strong></p><p><strong>Oxandrolone Augmentation of Resistance Training in Older Women: A Randomized Trial. Med Sci Sports Exerc. <a href="http://journals.lww.com/acsm-msse/Abstract/publishahead/Oxandrolone_Augmentation_of_Resistance_Training_in.97766.aspx" target="_blank">http://journals.lww.com/acsm-msse/Abstract/publishahead/Oxandrolone_Augmentation_of_Resistance_Training_in.97766.aspx</a> </strong></p><p></p><p></p><p>INTRODUCTION: Sarcopenia is disproportionately present in older women with disability, and optimum treatment is not clear. We conducted a double-blind, randomized, placebo-controlled trial to determine if oxandrolone administration in elderly women improves body composition or physical function beyond that which occurs in response to progressive resistance training.</p><p></p><p></p><p>METHODS: Twenty-nine sedentary women (aged 74.9+/-6.8yrs; 5.9+/-2.8 meds/day) were randomized to receive high intensity progressive resistance training (3 times/week for 12 weeks) combined with either oxandrolone (10 mg/day) or an identical placebo. Peak strength was assessed for leg press, chest press, triceps, knee extension and knee flexion. Power was assessed for leg press and chest press. Physical function measures included static and dynamic balance, chair rise, stair climb, gait speed and six-minute walk test. Body composition was assessed using dual energy X-ray absorptiometry.</p><p></p><p></p><p>RESULTS: Oxandrolone treatment augmented increases in lean tissue for the whole body (2.6kg; 95% CI 1.0, 4.2kg; p=0.003); arms (0.3kg; 95% CI 0.1, 0.5kg; p=0.001); legs (0.8kg; 95% CI 0.1, 1.4kg; p=0.018) and trunk (1.4kg; 95% CI 0.4, 2.3kg; p=0.004). Oxandrolone also augmented loss of fat tissue of the whole body (-1kg; 95% CI -1.6, -0.4, p=0.002), arms (-0.2kg; 95% CI -0.5, -0.02kg; p=0.032), legs (-0.4kg; 95% CI -0.6, -0.1; p=0.009) and tended to reduce trunk fat (-0.4kg; 95% CI -0.9, 0.04; p=0.07). Improvements in muscle strength and power, chair stand, and dynamic balance were all significant over time (p<0.05), but not different between groups (p>0.05).</p><p></p><p></p><p>CONCLUSION: Oxandrolone improves body composition adaptations to progressive resistance training in older women over 12 weeks without augmenting muscle function or functional performance beyond that of PRT alone.</p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 17585, member: 3"] Mavros Y, O'Neill E, Connerty M, Bean JF, Broe K, et al. [B] Oxandrolone Augmentation of Resistance Training in Older Women: A Randomized Trial. Med Sci Sports Exerc. [URL]http://journals.lww.com/acsm-msse/Abstract/publishahead/Oxandrolone_Augmentation_of_Resistance_Training_in.97766.aspx[/URL] [/B] INTRODUCTION: Sarcopenia is disproportionately present in older women with disability, and optimum treatment is not clear. We conducted a double-blind, randomized, placebo-controlled trial to determine if oxandrolone administration in elderly women improves body composition or physical function beyond that which occurs in response to progressive resistance training. METHODS: Twenty-nine sedentary women (aged 74.9+/-6.8yrs; 5.9+/-2.8 meds/day) were randomized to receive high intensity progressive resistance training (3 times/week for 12 weeks) combined with either oxandrolone (10 mg/day) or an identical placebo. Peak strength was assessed for leg press, chest press, triceps, knee extension and knee flexion. Power was assessed for leg press and chest press. Physical function measures included static and dynamic balance, chair rise, stair climb, gait speed and six-minute walk test. Body composition was assessed using dual energy X-ray absorptiometry. RESULTS: Oxandrolone treatment augmented increases in lean tissue for the whole body (2.6kg; 95% CI 1.0, 4.2kg; p=0.003); arms (0.3kg; 95% CI 0.1, 0.5kg; p=0.001); legs (0.8kg; 95% CI 0.1, 1.4kg; p=0.018) and trunk (1.4kg; 95% CI 0.4, 2.3kg; p=0.004). Oxandrolone also augmented loss of fat tissue of the whole body (-1kg; 95% CI -1.6, -0.4, p=0.002), arms (-0.2kg; 95% CI -0.5, -0.02kg; p=0.032), legs (-0.4kg; 95% CI -0.6, -0.1; p=0.009) and tended to reduce trunk fat (-0.4kg; 95% CI -0.9, 0.04; p=0.07). Improvements in muscle strength and power, chair stand, and dynamic balance were all significant over time (p<0.05), but not different between groups (p>0.05). CONCLUSION: Oxandrolone improves body composition adaptations to progressive resistance training in older women over 12 weeks without augmenting muscle function or functional performance beyond that of PRT alone. [/QUOTE]
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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
Anavar (Oxandrolone) Blood Levels Increased by Caffeine
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