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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Anastrozole Cognitive Impairment
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<blockquote data-quote="optimizely" data-source="post: 129683" data-attributes="member: 22230"><p>By bottom out, I meant dropping my E2 drastically lower than my SHBG which is 15.9. I upped my adex dosage in hopes of feeling better and getting my estradiol closer to my SHBG. On my last set of labs 6 weeks in I was on 16mg test daily and .25mg of adex EOD. Below are my 6 week labs:</p><p></p><p>TT: 912.3</p><p>FT: 30.1</p><p>SHBG: 15.9</p><p>E2 Sensitive: 19.8</p><p></p><p>I upped my arimidex to .25mg ed and lowered my daily test dosage to 13.75 daily based on my sensitive E2 and FT numbers.</p><p></p><p>I’m now 12 weeks in and feel worse than when I was 6 weeks in. I feel cognitively slower, issues with forming sentences and carry conversation, lack of libido, and ED. I was hoping my adjusts (lowering daily cyp dose and increasing adex dose) based on my blood work would have made me dialed-in. It feels like the opposite. I’m wondering if anastrozole the drug itself and taking it everyday may cause cognitive impairment (as I’ve read numerous studies on it causing cognitive impairment in women cancer patients taking at least 1mg per day for 3 months) or if I simply drove my E2 too low which is causing these side effects. Stuck on how I should proceed. I do agree a blood test is in order. But, in the meantime should I continue with the AI or hold off.</p></blockquote><p></p>
[QUOTE="optimizely, post: 129683, member: 22230"] By bottom out, I meant dropping my E2 drastically lower than my SHBG which is 15.9. I upped my adex dosage in hopes of feeling better and getting my estradiol closer to my SHBG. On my last set of labs 6 weeks in I was on 16mg test daily and .25mg of adex EOD. Below are my 6 week labs: TT: 912.3 FT: 30.1 SHBG: 15.9 E2 Sensitive: 19.8 I upped my arimidex to .25mg ed and lowered my daily test dosage to 13.75 daily based on my sensitive E2 and FT numbers. I’m now 12 weeks in and feel worse than when I was 6 weeks in. I feel cognitively slower, issues with forming sentences and carry conversation, lack of libido, and ED. I was hoping my adjusts (lowering daily cyp dose and increasing adex dose) based on my blood work would have made me dialed-in. It feels like the opposite. I’m wondering if anastrozole the drug itself and taking it everyday may cause cognitive impairment (as I’ve read numerous studies on it causing cognitive impairment in women cancer patients taking at least 1mg per day for 3 months) or if I simply drove my E2 too low which is causing these side effects. Stuck on how I should proceed. I do agree a blood test is in order. But, in the meantime should I continue with the AI or hold off. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Anastrozole Cognitive Impairment
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