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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Anastrozole 1mg daily?!?
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<blockquote data-quote="Cataceous" data-source="post: 163966" data-attributes="member: 38109"><p>In research on AI monotherapy it's been claimed that there's incomplete suppression of estradiol in men. I've wondered about that, including whether immunoassays were used, which tend to read high. In this case though we might posit that maintenance of normal LH levels allows for a reasonable amount of intratesticular aromatization, which we know is resistant to AI use. HPTA activity is maintained here because of the suppression of estradiol. Estradiol provides a lot of the negative feedback that normally suppresses LH production under TRT; artificially reducing the otherwise excessive estradiol allows LH levels to be maintained.</p><p></p><p>Addition: now that I think about it, the same thing is happening in AI monotherapy. The estradiol is probably created intratesticularly.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 163966, member: 38109"] In research on AI monotherapy it's been claimed that there's incomplete suppression of estradiol in men. I've wondered about that, including whether immunoassays were used, which tend to read high. In this case though we might posit that maintenance of normal LH levels allows for a reasonable amount of intratesticular aromatization, which we know is resistant to AI use. HPTA activity is maintained here because of the suppression of estradiol. Estradiol provides a lot of the negative feedback that normally suppresses LH production under TRT; artificially reducing the otherwise excessive estradiol allows LH levels to be maintained. Addition: now that I think about it, the same thing is happening in AI monotherapy. The estradiol is probably created intratesticularly. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Anastrozole 1mg daily?!?
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