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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
An Observation on Cream and Shots
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<blockquote data-quote="tropicaldaze1950" data-source="post: 250476" data-attributes="member: 13651"><p>I'm trying compounded topical 10% cream on the back of my neck/nape. When I applied it to the scrotum, I experienced prostate/bladder discomfort. We'll see. Labs in a month.</p><p></p><p></p><p>Methods Find Exp Clin Pharmacol</p><p></p><p>. 2000 Mar;22(2):129-33.</p><p> doi: 10.1358/mf.2000.22.2.796082.</p><h3>The pilosebaceous unit: a pivotal route for topical drug delivery</h3><p><a href="https://pubmed.ncbi.nlm.nih.gov/?term=Agarwal+R&cauthor_id=10849897" target="_blank">R Agarwal</a> <a href="https://pubmed.ncbi.nlm.nih.gov/10849897/#affiliation-1" target="_blank">1</a>, <a href="https://pubmed.ncbi.nlm.nih.gov/?term=Katare+OP&cauthor_id=10849897" target="_blank">O P Katare</a>, <a href="https://pubmed.ncbi.nlm.nih.gov/?term=Vyas+SP&cauthor_id=10849897" target="_blank">S P Vyas</a></p><p>Affiliations expand</p><ul> <li data-xf-list-type="ul">PMID: <strong>10849897</strong></li> <li data-xf-list-type="ul">DOI: <a href="https://doi.org/10.1358/mf.2000.22.2.796082" target="_blank">10.1358/mf.2000.22.2.796082</a></li> </ul><h3>Abstract</h3><p>The hair follicle, hair shaft and sebaceous gland are collectively known as the pilosebaceous unit. The pilosebaceous unit is a complex, dynamic, 3-D structure, which is the site of unique biochemical, metabolical and immunological events. Ongoing research has focused on the hair follicle as a potential route for both localized and systemic drug delivery. Targeted drug delivery to the specific sites of hair follicle has paved ways to treat several dermatological abnormalities that are known to originate at the hair follicle. In recent studies, topical liposomes have been shown to target the drug to the pilosebaceous unit. This review describes general aspects of pilosebaceous unit, follicular delivery, with particular emphasis on studies which have demonstrated targeted follicular delivery via liposomes.</p></blockquote><p></p>
[QUOTE="tropicaldaze1950, post: 250476, member: 13651"] I'm trying compounded topical 10% cream on the back of my neck/nape. When I applied it to the scrotum, I experienced prostate/bladder discomfort. We'll see. Labs in a month. Methods Find Exp Clin Pharmacol . 2000 Mar;22(2):129-33. doi: 10.1358/mf.2000.22.2.796082. [HEADING=2]The pilosebaceous unit: a pivotal route for topical drug delivery[/HEADING] [URL='https://pubmed.ncbi.nlm.nih.gov/?term=Agarwal+R&cauthor_id=10849897']R Agarwal[/URL] [URL='https://pubmed.ncbi.nlm.nih.gov/10849897/#affiliation-1']1[/URL], [URL='https://pubmed.ncbi.nlm.nih.gov/?term=Katare+OP&cauthor_id=10849897']O P Katare[/URL], [URL='https://pubmed.ncbi.nlm.nih.gov/?term=Vyas+SP&cauthor_id=10849897']S P Vyas[/URL] Affiliations expand [LIST] [*]PMID: [B]10849897[/B] [*]DOI: [URL='https://doi.org/10.1358/mf.2000.22.2.796082']10.1358/mf.2000.22.2.796082[/URL] [/LIST] [HEADING=2]Abstract[/HEADING] The hair follicle, hair shaft and sebaceous gland are collectively known as the pilosebaceous unit. The pilosebaceous unit is a complex, dynamic, 3-D structure, which is the site of unique biochemical, metabolical and immunological events. Ongoing research has focused on the hair follicle as a potential route for both localized and systemic drug delivery. Targeted drug delivery to the specific sites of hair follicle has paved ways to treat several dermatological abnormalities that are known to originate at the hair follicle. In recent studies, topical liposomes have been shown to target the drug to the pilosebaceous unit. This review describes general aspects of pilosebaceous unit, follicular delivery, with particular emphasis on studies which have demonstrated targeted follicular delivery via liposomes. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
An Observation on Cream and Shots
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