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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
AI's and joint pain
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<blockquote data-quote="FunkOdyssey" data-source="post: 233173" data-attributes="member: 44064"><p>At the risk of parroting Bossa and friends, are you aware that serum levels of E2 may not reflect the E2 available to a particular tissue? Each tissue that depends on E2 converts it locally from T with a quantity of aromatase that is specific to the tissue and its requirements. It is then possible that you could take an AI and create a local deficiency of E2 in your joints that is not reflected in the serum E2 measurements.</p><p></p><p>If you've already proven that daily dosing works well for you except for the inconvenience, could you not return to daily for a limited time and drop the AI to test this hypothesis?</p></blockquote><p></p>
[QUOTE="FunkOdyssey, post: 233173, member: 44064"] At the risk of parroting Bossa and friends, are you aware that serum levels of E2 may not reflect the E2 available to a particular tissue? Each tissue that depends on E2 converts it locally from T with a quantity of aromatase that is specific to the tissue and its requirements. It is then possible that you could take an AI and create a local deficiency of E2 in your joints that is not reflected in the serum E2 measurements. If you've already proven that daily dosing works well for you except for the inconvenience, could you not return to daily for a limited time and drop the AI to test this hypothesis? [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
AI's and joint pain
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