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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Advice on whether or not to start TRT or look for other causes
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<blockquote data-quote="madman" data-source="post: 272398" data-attributes="member: 13851"><p>Forget getting caught up on comparing assays/reference ranges between all the different labs.</p><p></p><p>As I have stated numerous times on the forum always test using the same lab/assay (most accurate) TT (LC/MS-MS) and FT (Equilibrium Dialysis or Equilibrium Ultrafiltration) especially in cases of altered SHBG!</p><p></p><p>If you do not have access to such (highly doubtful) if you live in the US then you will need to use/rely upon the cFTV.</p><p></p><p>Keep in mind as of now cFTV tends to overestimate somewhat when compared against the gold-standard Equilibrium Dialysis so your FT may very well be somewhat lower.</p><p></p><p>As you can see your FT using what would be considered the most accurate assay is just above the bottom end of the reference range.</p><p></p><p>Your FT level is dismal and far from what would be considered healthy.</p><p></p><p>Although you are hitting a robust TT 637 ng/dL your SHBG is absurdly high at 80 nmol/L which has your FT close to being in the gutter!</p><p></p><p></p><p></p><p></p><p><strong><em>Look over post #11</em></strong></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/direct-measurements-of-free-hormones-using-mass-spectrometry-based-methods.28144/[/URL]</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/very-high-free-test-at-9mg-test-per-day.28522/#post-265454[/URL]</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/a-high-throughput-method-for-accurate-measurement-of-ft-in-serum-using-ed-coupled-with-id-uhplc-ms-ms.28949/#post-270819[/URL]</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/discrepancies-in-four-algorithms-for-the-calculation-of-free-and-bioavailable-t.28865/[/URL]</p></blockquote><p></p>
[QUOTE="madman, post: 272398, member: 13851"] Forget getting caught up on comparing assays/reference ranges between all the different labs. As I have stated numerous times on the forum always test using the same lab/assay (most accurate) TT (LC/MS-MS) and FT (Equilibrium Dialysis or Equilibrium Ultrafiltration) especially in cases of altered SHBG! If you do not have access to such (highly doubtful) if you live in the US then you will need to use/rely upon the cFTV. Keep in mind as of now cFTV tends to overestimate somewhat when compared against the gold-standard Equilibrium Dialysis so your FT may very well be somewhat lower. As you can see your FT using what would be considered the most accurate assay is just above the bottom end of the reference range. Your FT level is dismal and far from what would be considered healthy. Although you are hitting a robust TT 637 ng/dL your SHBG is absurdly high at 80 nmol/L which has your FT close to being in the gutter! [B][I]Look over post #11[/I][/B] [URL unfurl="true"]https://www.excelmale.com/forum/threads/direct-measurements-of-free-hormones-using-mass-spectrometry-based-methods.28144/[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/very-high-free-test-at-9mg-test-per-day.28522/#post-265454[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/a-high-throughput-method-for-accurate-measurement-of-ft-in-serum-using-ed-coupled-with-id-uhplc-ms-ms.28949/#post-270819[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/discrepancies-in-four-algorithms-for-the-calculation-of-free-and-bioavailable-t.28865/[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Advice on whether or not to start TRT or look for other causes
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