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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Advice on low dose daily testosterone
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<blockquote data-quote="Cataceous" data-source="post: 204839" data-attributes="member: 38109"><p>It's important to distinguish between fast metabolism and fast absorption. Fast metabolism has essentially nothing to do with the apparent half-life of an injected testosterone ester, in which the ester is slowly released from the depot over time. Someone with unusually fast metabolism of testosterone would notice that his total testosterone is proportionally lower at all times compared to someone with normal metabolism who is otherwise identical. The rates of decline of serum testosterone will be the same for the two if they are absorbing the testosterone ester at the same rate. For example, in five days the normal metabolizer sees his serum testosterone drop from 1,000 ng/dL to 500 ng/dL. Meanwhile, in five days the fast metabolizer sees his testosterone drop from 500 ng/dL to 250 ng/dL. </p><p></p><p>On the other hand, someone who absorbs much faster than usual will see a shorter apparent half-life in his serum testosterone. For example, his levels on testosterone cypionate might drop by half in two days, compared to the more typical five days. The fast absorber is the one who clearly benefits from a higher injection frequency if he needs more stable serum testosterone.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 204839, member: 38109"] It's important to distinguish between fast metabolism and fast absorption. Fast metabolism has essentially nothing to do with the apparent half-life of an injected testosterone ester, in which the ester is slowly released from the depot over time. Someone with unusually fast metabolism of testosterone would notice that his total testosterone is proportionally lower at all times compared to someone with normal metabolism who is otherwise identical. The rates of decline of serum testosterone will be the same for the two if they are absorbing the testosterone ester at the same rate. For example, in five days the normal metabolizer sees his serum testosterone drop from 1,000 ng/dL to 500 ng/dL. Meanwhile, in five days the fast metabolizer sees his testosterone drop from 500 ng/dL to 250 ng/dL. On the other hand, someone who absorbs much faster than usual will see a shorter apparent half-life in his serum testosterone. For example, his levels on testosterone cypionate might drop by half in two days, compared to the more typical five days. The fast absorber is the one who clearly benefits from a higher injection frequency if he needs more stable serum testosterone. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Advice on low dose daily testosterone
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