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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Adjusting my dose down for longterm health reasons, will it lead to muscle loss?
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<blockquote data-quote="Wilson7" data-source="post: 210230" data-attributes="member: 39729"><p>I've asked several docs that have been using ND in practice for everything from HIV to HRT and not one has had concerns about cardio toxicity or has seen it in practice in therapeutic dosing. Sure there are animal studies, where are the human studies to support them? We have data from cross-sectional analysis of wannabe genetically altered farm animal look alikes taking high doses of multiple drugs, that doesn't tell us anything about therapeutic dosing esp for HRT ND/TC that is long term. 150TC/75ND is more than enough for HRT, top end borderline supraphysiological, sure don't need more than that. If you are truly concerned about cardiotoxicity, get an echo and a CT angiogram, and/or LGE cardiac MRI to assess fibrosis. See where you stand, you'd be the perfect N of 1 given your history esp if you have no family history. IMO, either an ARB or ACEi should be taken by anyone either abusing AAS or even on TRT (old guys), always prescribed as there is the risk of angioedema in some populations. ANGII and ALD are the players in LVH and fibrosis, and HTN.</p></blockquote><p></p>
[QUOTE="Wilson7, post: 210230, member: 39729"] I've asked several docs that have been using ND in practice for everything from HIV to HRT and not one has had concerns about cardio toxicity or has seen it in practice in therapeutic dosing. Sure there are animal studies, where are the human studies to support them? We have data from cross-sectional analysis of wannabe genetically altered farm animal look alikes taking high doses of multiple drugs, that doesn't tell us anything about therapeutic dosing esp for HRT ND/TC that is long term. 150TC/75ND is more than enough for HRT, top end borderline supraphysiological, sure don't need more than that. If you are truly concerned about cardiotoxicity, get an echo and a CT angiogram, and/or LGE cardiac MRI to assess fibrosis. See where you stand, you'd be the perfect N of 1 given your history esp if you have no family history. IMO, either an ARB or ACEi should be taken by anyone either abusing AAS or even on TRT (old guys), always prescribed as there is the risk of angioedema in some populations. ANGII and ALD are the players in LVH and fibrosis, and HTN. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Adjusting my dose down for longterm health reasons, will it lead to muscle loss?
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