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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Adipsia/Complete Loss of Thirst + Skin Elasticity Changes
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<blockquote data-quote="madman" data-source="post: 196430" data-attributes="member: 13851"><p>You were started on a whopping dose of testosterone 200 mg/week.</p><p></p><p>Most men on trt are injecting 100-200 mg/week and some <100mg/week and even then many would never need the higher end doses to achieve a healthy FT level.</p><p></p><p>Sure some men do need the higher-end doses but it is far from common.</p><p></p><p>Unfortunately, many men on trt are overmedicated.</p><p></p><p>Although we have no idea when blood work was done it is clear as day that your TT>1500 is through the roof let alone FT is high and unfortunately may very well be much higher than you think as it is doubtful that you had it tested using an accurate assay such as Equilibrium Dialysis or Ultrafiltration.</p><p></p><p>Although TT is important to know FT is what truly matters as it is the active unbound fraction of testosterone responsible for the positive effects.</p><p></p><p>When testing it is critical to use the most accurate assays TT/estradiol/DHT (LC/MS-MS) and FT (Equilibrium Dialysis or Ultrafiltration).</p><p></p><p>Knowing where your hormones sit on such protocol (dose T/injection frequency) is critical.</p><p></p><p>Everyone gets too caught up on where their TT level sits and again although important to know FT is what you should be more concerned with.</p><p></p><p>The only way to know where your FT truly sits is to have it tested using the most accurate assays such as the gold standard Equilibrium Dialysis or Ultrafiltration (next best).</p><p></p><p>Regardless of looking over your labs if they were done a few days after your injection then absurdly high TT/FT levels would be expected when injecting a whopping dose of T 200 mg once weekly.</p><p></p><p>If labs were done at the true trough (7 days post-injection) just before your following weekly injection then your TT/FT levels are horribly high!</p><p></p><p>The downfall of injecting large doses of T once weekly is that your peak levels 8-12 hrs post-injection and during the first few days will be absurdly high only to be followed by much lower levels come weeks end which can have a negative effect on energy/mood/libido/erections.</p><p></p><p>There will be an extreme between peak--->trough levels throughout the week!</p><p></p><p>Top it all off that we have no idea where your SHBG sits which is important to know as it will have a big impact on your FT level let alone can play a big role in what injection frequency may suit you best.</p><p></p><p>Androgens increase the retention of electrolytes and you are most likely retaining water.</p><p></p><p>Most men will gain 5-10 lbs of water weight as in extra-cellular between muscle/skin (bloat/puffiness) and intracellular inside muscle cell (water/glycogen) within the first 4 weeks of starting trt.</p><p></p><p>Where does your RBCs/hemoglobin/hematocrit sit?</p><p></p><p>Keep in mind that exogenous T will drive up one's RBCs/hemoglobin/hematocrit within the first month and can take anywhere from 9-12 months to reach peak levels.</p><p></p><p></p><p></p><p>These are the assays you want to use when testing FT.</p><p></p><p>Either will suffice.</p><p></p><p>Both tests also include TT (LC/MS-MS).</p><p></p><p>1. <a href="https://www.discountedlabs.com/hematocrit-total-and-free-testosterone-1500-ng-dl" target="_blank">Testosterone, Total and Free (NO Upper Limit) plus Hematocrit</a></p><p></p><p>2. <a href="https://www.discountedlabs.com/testosterone-free-dialysis-and-total-ls-ms-ms" target="_blank">Testosterone, Total, LC/MS and Free (Equilibrium Ultrafiltration)</a></p></blockquote><p></p>
[QUOTE="madman, post: 196430, member: 13851"] You were started on a whopping dose of testosterone 200 mg/week. Most men on trt are injecting 100-200 mg/week and some <100mg/week and even then many would never need the higher end doses to achieve a healthy FT level. Sure some men do need the higher-end doses but it is far from common. Unfortunately, many men on trt are overmedicated. Although we have no idea when blood work was done it is clear as day that your TT>1500 is through the roof let alone FT is high and unfortunately may very well be much higher than you think as it is doubtful that you had it tested using an accurate assay such as Equilibrium Dialysis or Ultrafiltration. Although TT is important to know FT is what truly matters as it is the active unbound fraction of testosterone responsible for the positive effects. When testing it is critical to use the most accurate assays TT/estradiol/DHT (LC/MS-MS) and FT (Equilibrium Dialysis or Ultrafiltration). Knowing where your hormones sit on such protocol (dose T/injection frequency) is critical. Everyone gets too caught up on where their TT level sits and again although important to know FT is what you should be more concerned with. The only way to know where your FT truly sits is to have it tested using the most accurate assays such as the gold standard Equilibrium Dialysis or Ultrafiltration (next best). Regardless of looking over your labs if they were done a few days after your injection then absurdly high TT/FT levels would be expected when injecting a whopping dose of T 200 mg once weekly. If labs were done at the true trough (7 days post-injection) just before your following weekly injection then your TT/FT levels are horribly high! The downfall of injecting large doses of T once weekly is that your peak levels 8-12 hrs post-injection and during the first few days will be absurdly high only to be followed by much lower levels come weeks end which can have a negative effect on energy/mood/libido/erections. There will be an extreme between peak--->trough levels throughout the week! Top it all off that we have no idea where your SHBG sits which is important to know as it will have a big impact on your FT level let alone can play a big role in what injection frequency may suit you best. Androgens increase the retention of electrolytes and you are most likely retaining water. Most men will gain 5-10 lbs of water weight as in extra-cellular between muscle/skin (bloat/puffiness) and intracellular inside muscle cell (water/glycogen) within the first 4 weeks of starting trt. Where does your RBCs/hemoglobin/hematocrit sit? Keep in mind that exogenous T will drive up one's RBCs/hemoglobin/hematocrit within the first month and can take anywhere from 9-12 months to reach peak levels. These are the assays you want to use when testing FT. Either will suffice. Both tests also include TT (LC/MS-MS). 1. [URL="https://www.discountedlabs.com/hematocrit-total-and-free-testosterone-1500-ng-dl"]Testosterone, Total and Free (NO Upper Limit) plus Hematocrit[/URL] 2. [URL="https://www.discountedlabs.com/testosterone-free-dialysis-and-total-ls-ms-ms"]Testosterone, Total, LC/MS and Free (Equilibrium Ultrafiltration)[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Adipsia/Complete Loss of Thirst + Skin Elasticity Changes
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