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General Health & Fitness
Health & Wellness
ACE and ARB blood pressure meds (i.e losartan) and coronavirus concern
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<blockquote data-quote="Marco N Cognito" data-source="post: 175347" data-attributes="member: 13"><p>Much of the controversy about the positive or negative effect of ARB/ACEI is based on a time confusion. The positive effect of ACE2 would only occur <strong>AFTER the SARS-CoV-2 entered into the target cells.</strong> On the opposite, <strong>BEFORE its entry, the ACE2 availability may potently increase the number of receptors for the virus spike proteins and leads to an enhanced severity of the infection.</strong> This is the conundrum I worry about. What we urgently need now is the ratio of death according to the use or not of ARB/ACEI among the patients with comorbidities (hypertension, diabetes, CVD).</p></blockquote><p></p>
[QUOTE="Marco N Cognito, post: 175347, member: 13"] Much of the controversy about the positive or negative effect of ARB/ACEI is based on a time confusion. The positive effect of ACE2 would only occur [B]AFTER the SARS-CoV-2 entered into the target cells.[/B] On the opposite, [B]BEFORE its entry, the ACE2 availability may potently increase the number of receptors for the virus spike proteins and leads to an enhanced severity of the infection.[/B] This is the conundrum I worry about. What we urgently need now is the ratio of death according to the use or not of ARB/ACEI among the patients with comorbidities (hypertension, diabetes, CVD). [/QUOTE]
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General Health & Fitness
Health & Wellness
ACE and ARB blood pressure meds (i.e losartan) and coronavirus concern
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