My take from someone who was on accutane in late teens. Stay clear of it. I had a host of hormone issues throughout life, ended up infertile and not able to have kids. Testosterone came back below 150 in my 20’s. Dramatic decline from about 18 to 25. At 18 I was very healthy and strong into pretty much any sport. I started trt at 25 and the only way trt made me feel good was mixing injection and gels. We proved through bloodwork my dht was always too low just on injection and the gels made up for it. I fully believe the accutane did something to my body to reduce testosterone and dht. I would recommend anyone living with acne( and mine was really bad) to just live with it because if there’s any chance you might experience what I did you’ll regret taking it. This product should not be marketed!