Reply to thread

Message

Actually, it is something you can buy and just start using, if you like. Rapa is available at ADC.

Interview with a doctor who's using (and prescribing) it now:
Interview
The doctor's website

Side effects (canker sores in mouth, etc.) appear to be linked to every-day dosing (for immune suppression, as is used to prevent organ rejection.) This may be because rapa has a long half-life in the body (62 ±16 hours), so daily dosing causes major spikes in blood levels as the peaks begin to stack.

Rapa anti-aging protocols call for dosing at weekly or longer intervals, providing an adequate wash-out period. (Interestingly, apparently rapa boosts the immune system when given at this cadence.)

<blockquote data-quote="SoCal Guy" data-source="post: 79583" data-attributes="member: 14529">Actually, it is something you can buy and just start using, if you like.&nbsp; Rapa is available at ADC.Interview with a doctor who&#039;s using (and prescribing) it now: &nbsp;<a href="http://roguehealthandfitness.com/rapamycin-anti-aging-medicine-an-interview-with-alan-s-green-m-d/" target="_blank">Interview</a>&nbsp;<a href="https://www.rapamycintherapy.com/" target="_blank">The doctor&#039;s website</a>Side effects (canker sores in mouth, etc.) appear to be linked to every-day dosing (for immune suppression, as is used to prevent organ rejection.) This may be because rapa has a long half-life in the body (62 ±16 hours), so daily dosing causes major spikes in blood levels as the peaks begin to stack.Rapa anti-aging protocols call for dosing at weekly or longer intervals, providing an adequate wash-out period. (Interestingly, apparently rapa boosts the immune system when given at this cadence.)</blockquote>

[QUOTE="SoCal Guy, post: 79583, member: 14529"] Actually, it [B]is [/B]something you can buy and just start using, if you like. Rapa is available at ADC. Interview with a doctor who's using (and prescribing) it now: [URL="http://roguehealthandfitness.com/rapamycin-anti-aging-medicine-an-interview-with-alan-s-green-m-d/"]Interview[/URL] [URL="https://www.rapamycintherapy.com/"]The doctor's website[/URL] Side effects (canker sores in mouth, etc.) appear to be linked to every-day dosing (for immune suppression, as is used to prevent organ rejection.) This may be because rapa has a long half-life in the body (62 [FONT=Roboto]±[/FONT]16 hours), so daily dosing causes major spikes in blood levels as the peaks begin to stack. Rapa anti-aging protocols call for dosing at weekly or longer intervals, providing an adequate wash-out period. (Interestingly, apparently rapa [B]boosts [/B]the immune system when given at this cadence.) [/QUOTE]

Verification

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038