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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
A different dosing strategy with bremelanotide (PT-141) yields dramatically better results
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<blockquote data-quote="electrify" data-source="post: 266445" data-attributes="member: 44439"><p>Probably better for another thread specifically on MIF-1, I'll make one soon in the Mental Health forum.</p><p></p><p>But I've done multiple cycles of it and each one is kinda different. The 1st one I did back in May I didn't even feel anything until like the 4th day when suddenly while at an outdoor mall I could feel that "vibe" again. This peak effect subsided but I still felt like my baseline was higher for some time until crashing later on for unrelated reasons.</p><p></p><p>No side effects. Its an amazing peptide for me. When I first did it though I started the first day at a smaller dose like 5 mg just to make sure no adverse effects. One might think "Oh because PT141 improves libido then MIF1 will lower it" but this is absolutely not true and in fact its a little the opposite because if anhedonia improves, libido improves for me anyways and MIF is dopaminergic after all (But I wouldn't expect it to improve libido for a non-anhedonic/blunted person)</p><p></p><p>I was feeling horribly numb in late August, I had crashed badly and I was getting very worried and in a dark place. I took MIF-1 and then within 2 hours felt it this last cycle. Suddenly the world was brighter, I felt a huge motivation and hedonic tone boost, could anticipate the future again, feel the sun out. This peak effect went down but I still came out of the cycle "reset" back to a copable point. It has a great effect on lowering stress-too. And while on it, the morning dread of the day (when my symptoms are worst) gets so much better.</p><p></p><p> It seems like I feel the effects earlier with each cycle. Know that MIF-1 the effects can actually go backwards if you take too much too long (this is mentioned in a study on the oral form), which is why its important to keep the schedule/dosing in accordance with that study. The longest I've done it is 8 mg for 8 days and when I did it on the 8th day things kinda went backward slightly. 5-7 days at most seemed ok for me. 6 days for me is the sweet spot. I believe its because it inhibits alpha-MSH and some is needed.</p><p></p><p>I did do bloodwork on my alpha-MSH before and at the end of one of my cycles though and it didn't go down that much just from 13 to 9.</p><p></p><p>Also I think MIF-1 should be used like a 'reset' opportunity. So literally exercise intense every single day you are on a cycle of MIF to make use of that dopamine to try to make it stick. Another thing I found is taking Mucuna Pruriens L-dopa supplement synergises with it (this is also in studies, MIF potentiates L-dopa).</p><p></p><p>LDN I stop while on MIF to avoid any interactions with opiod system (MIF-1 is kind of like a super LDN, its an opiod antagonist in ways I don't really get) , but afterwards, I notice my LDN endorphin rebound is stronger too for like a few days.</p><p></p><p>These days Ketamine IV is presented as the 'hot' thing for anhedonia but MIF1 was way way better for me.</p></blockquote><p></p>
[QUOTE="electrify, post: 266445, member: 44439"] Probably better for another thread specifically on MIF-1, I'll make one soon in the Mental Health forum. But I've done multiple cycles of it and each one is kinda different. The 1st one I did back in May I didn't even feel anything until like the 4th day when suddenly while at an outdoor mall I could feel that "vibe" again. This peak effect subsided but I still felt like my baseline was higher for some time until crashing later on for unrelated reasons. No side effects. Its an amazing peptide for me. When I first did it though I started the first day at a smaller dose like 5 mg just to make sure no adverse effects. One might think "Oh because PT141 improves libido then MIF1 will lower it" but this is absolutely not true and in fact its a little the opposite because if anhedonia improves, libido improves for me anyways and MIF is dopaminergic after all (But I wouldn't expect it to improve libido for a non-anhedonic/blunted person) I was feeling horribly numb in late August, I had crashed badly and I was getting very worried and in a dark place. I took MIF-1 and then within 2 hours felt it this last cycle. Suddenly the world was brighter, I felt a huge motivation and hedonic tone boost, could anticipate the future again, feel the sun out. This peak effect went down but I still came out of the cycle "reset" back to a copable point. It has a great effect on lowering stress-too. And while on it, the morning dread of the day (when my symptoms are worst) gets so much better. It seems like I feel the effects earlier with each cycle. Know that MIF-1 the effects can actually go backwards if you take too much too long (this is mentioned in a study on the oral form), which is why its important to keep the schedule/dosing in accordance with that study. The longest I've done it is 8 mg for 8 days and when I did it on the 8th day things kinda went backward slightly. 5-7 days at most seemed ok for me. 6 days for me is the sweet spot. I believe its because it inhibits alpha-MSH and some is needed. I did do bloodwork on my alpha-MSH before and at the end of one of my cycles though and it didn't go down that much just from 13 to 9. Also I think MIF-1 should be used like a 'reset' opportunity. So literally exercise intense every single day you are on a cycle of MIF to make use of that dopamine to try to make it stick. Another thing I found is taking Mucuna Pruriens L-dopa supplement synergises with it (this is also in studies, MIF potentiates L-dopa). LDN I stop while on MIF to avoid any interactions with opiod system (MIF-1 is kind of like a super LDN, its an opiod antagonist in ways I don't really get) , but afterwards, I notice my LDN endorphin rebound is stronger too for like a few days. These days Ketamine IV is presented as the 'hot' thing for anhedonia but MIF1 was way way better for me. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
A different dosing strategy with bremelanotide (PT-141) yields dramatically better results
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