*The lack of positive effects from CM supplementation within the existing literature is due to a number of factors, including the testing protocols not featuring a predominantly aerobic energy contribution, the lack of test-retest reliability of exercise protocols, dosing strategy (i.e., amount and timing), and the recent discovery of quality control issues with some manufacturers stated citrulline: malate ratios
*From the available evidence, an acute 8 g dose CM may, albeit not consistently, increase muscular endurance-strength performance (Table 1)
*There is little evidence to advocate its use in the production and maintenance of muscular power, maximal strength, recovery of muscular function, or supporting muscular adaptations currently (Table 1)
*Athletes wishing to explore NO enhancers are reminded that a good level of evidence exists for L-citrulline to improve exercise performance, and therefore may consider the use of this supplement whilst the intricacies of CM supplementation are discovered
*Furthermore, manufacturers are required to take more responsibility to guarantee that the ratio stated is what is contained within the product and researchers/practitioners should be aware of this when sourcing their product for research and/or use with athletes
*Finally, those who have the resources (primarily manufacturers but also researchers) should analyze the purity of the C:M ratio to ensure they have every opportunity of achieving an ergogenic effect
