There's a number of issues here. First of all, your estradiol was measured with the incorrect test. Men should only evaluate their e2 with the LC, MS/MS (sensitive, also known as ultrasensitive) test. The reference range you provided for your estradiol is a dead giveaway that your doctor ordered the incorrect test. That means you can't rely on the results you have, they are typically inflated. Healthy estradiol levels are necessary for a man: it's a critical hormone, not a waste product.
Now, your protocol. Why in the world are you on a whopper of a dose? That's a once a week injection?
Finally, your PSA did climb quickly, which is typical of prostatitis, not prostate cancer. It should certainly be addressed, but stopping TRT at this point would be premature.
