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Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
9 months into Clomiphene treatment for low test
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<blockquote data-quote="Cataceous" data-source="post: 198477" data-attributes="member: 38109"><p>It's a plausible hypothesis: Enclomiphene blocks certain estrogen receptors. Estrogen contributes to libido. Therefore enclomiphene could harm libido. However, even if there's something to this it's still not a black and white issue. Some guys do well long-term on modest doses of Clomid. I've been on enclomiphene with TRT for over a year and libido is better than during most of the previous years on TRT.</p><p></p><p>It's also possible to create other hypotheses that would need to be tested. For example: Zuclomiphene is estrogenic. Estrogens tend to raise prolactin. Elevated prolactin can harm libido independently of testosterone levels. Therefore Clomid could harm libido. Yet another hypothesis would say that excessive estrogenic effects alone are a problem; zuclomiphene combines with higher naturally produced estradiol yielding a double-whammy. This proposition is more tenuous given the known positive association between estradiol and libido. Yet there may be limits above which estradiol reduces libido, or alternatively, the ratio of estradiol to testosterone may be the parameter that grows too large with Clomid use.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 198477, member: 38109"] It's a plausible hypothesis: Enclomiphene blocks certain estrogen receptors. Estrogen contributes to libido. Therefore enclomiphene could harm libido. However, even if there's something to this it's still not a black and white issue. Some guys do well long-term on modest doses of Clomid. I've been on enclomiphene with TRT for over a year and libido is better than during most of the previous years on TRT. It's also possible to create other hypotheses that would need to be tested. For example: Zuclomiphene is estrogenic. Estrogens tend to raise prolactin. Elevated prolactin can harm libido independently of testosterone levels. Therefore Clomid could harm libido. Yet another hypothesis would say that excessive estrogenic effects alone are a problem; zuclomiphene combines with higher naturally produced estradiol yielding a double-whammy. This proposition is more tenuous given the known positive association between estradiol and libido. Yet there may be limits above which estradiol reduces libido, or alternatively, the ratio of estradiol to testosterone may be the parameter that grows too large with Clomid use. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
9 months into Clomiphene treatment for low test
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