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I'm a 37 year old who's been on TRT for 5 weeks.  Before I met with the Dr., I had blood work done (female hormone panel from privatemdlabs) and my Test was 317 and Estradiol was 37.7.


The Dr. gave me Testosterone Cypionate and said inject 1-2CC's weekly.  At the office on my first visit, he gave me 2CC's (400mg), so I keep that up for another 4 weeks.


I had my blood work done again (same test as before) and my test totals are >1500 and Estradiol is 118.6.


My nipples are sensitive and I'm having trouble maintaining an erection.  I also do not get morning wood.  I had the same erection issues before starting TRT.


I feel my estradiol is way too high.  I do not have a prescription for an estrogen blocker, but the doc did say he'd prescribe one if necessary while we talked during the initial visit.


I plan to reduce my shot to 1CC/200mg per week for 5-6 weeks and then redo the blood work.


Does that sound like a reasonable plan?  If not, what would you change?


TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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